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9 Cards in this Set
- Front
- Back
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What is the pathology of toxic multinodular goiter?
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Focal patches of hyperfunctioning follicular cells working independently of TSH from mutation in TSH receptor
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What does the mutation in TSH receptor cause?
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Increase release of T3/T4
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What is the Jod-Basedow pheomenon?
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Thyrotoxicosis if a patient with iodine deficiency goiter is made iodine replete
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What is the pathology of Graves' Disease?
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Autoimmune hyperthyroidism with thyroid-stimulating immunoglobulins
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What are some findings of Graves' disease?
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Proptosis, EOM swelling, pretibial myxedema, inc in CT deposition, diffuse goiter
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When does Graves' disease usually present?
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Stress (childbirth)
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What is the pathology of Thyroid Storm?
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Stress induced catecholamine surge leading to death by arrhythmia
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What is a lab finding of Thyroid Storm?
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Inc Alk Phos from increased bone turnover
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How do you treat Thyroid Storm?
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Propranolol
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