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20 Cards in this Set

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A-90. Define the locations of Zenker's, Traction, and Epiphrenic esophageal diverticula?
Zencker: above upper esophageal sphincter

Traction: midpoint of esophagus

Epiphrenic: above the lower esopahgeal sphincter
A-90. Describe Chronic Type A gastritis, its cause, clin pres, and associations.
Grandular destruction and mucosal atrophy

Autoimmune Ab against gastric glands, parietal cells, and IF

Cause pernicious anemia (lack IF) and associated with Hashimot's, Addison's Dz, and Vitiligo
A-90. Hyperplastic polyps are the most_______, common in those age_____, caused by_____, and have______ risk of becoming cancerous.
Common - 50s and 60s - little to no risk for malignancy

Due to decreased epithelial cell turnover and accumulation of mature cells on the surface
A-90. Describe a villous adenoma?
Has finger-like projections, common to in rectum/sigmoid colon, usually cause gross rectal bleeding
A-90. What's Peutz-Jeghers Syndrome and how does it present?
Inherited auto dom hamartomatous polyp disorder that is FPS of the entire bowel

Hyperpigmentation lips, palms, and soles - low cancer potential
A-90. A form of classic FAP with FAP colon polyps, malignant brain tumors, auto dom, high risk of polyps being cancerous....what is this dz?
Turcot's Syndrome
A-90. S/S of colon cancer?
Most asymptomatic until late in their course

Right colonic cancer: iron def, +hemocult stool, no stool changes

Left Colonic: +hemocult, change in bowel habits, and crampy LLQ pain, "penicl stools"
A-90. What GI dz leaves blood vessels more exposed, + hemocult and gross bleeding, and is painless?
Diverticulosis
A-90. What causes diverticulitis?
Inflammation of diverticuli due to small particles like seeds, nuts, etc, LLQP, -hemocult, can cause sepsis
A-90. C & C Crohn's Dz and Ulcerative Colitis.
C Dz: rectum spared, skip lesions, transmural, non-caseating granulomas, crypt abscess, strictures, fissures, and distulas, + string sign on XR

UC: starts at rectum, cont lesions, mucosa/submucosa only, nongranu lesions, crypt absc, pseudopolyps, lead pipe colon
A-90. What test is the gold standard for malabsorption issues?
Stool Fat Analysis
A-90. What dz affects the small intestine, has "flat villi," anti-gliadin, gluten, endomysial Ab, and reticulum, and are at risk for MALT?
Celiac Spure
A-90. What is the cause and S/S of choledocholithiasis?
Obstruction of common bile duct

Clay-colored stool, tea colored urine, elevated alkaline phosphatase and conjugated bilirubin
A-90. What causes Primary Sclerosing Cholangitis and who is at risk?
Non-infectious inflammation and sclerosis of bile ducts with eventual obliteration of all biliary ducts

Patients with hx of inflammatory bowel dz
A-90. What enzyme conjugates bilirubin?
Uridine Disphosphate Glucuronosyl Transderase
A-90. What is the difference between type I and II Crigler-Najjar dz?
Type 1: absent UGT, no conjugation, lethal

Type 2: decreased UGT with chroninc elevation of unconj. bilirubin
A-90. How do can you tell acute from late HAV?
Acute: HAV IgM

Late: HAV IgG
A-90. What is the source of HCV, labs, and epi?
RNA Virus (flavivirus)

Episodic increases in AST/ALT

Most common cause of transfusion hepatitis
A-90. In the hepatitis window period, what two tests will be negative?
HBsAG and anti-HBs
A-90. Intracytoplasmic eosinophilic hyaline inclusion are seen in?
Alcoholic Cirrhosis