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8 Cards in this Set
- Front
- Back
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A-84. What drugs inhibit the 50s and 30s ribosomal subunits in bacteria?
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50s: "CEC" Chloramphenicol - Erythromycin - Clindamycin
30s: "TA" Tetracycline - Aminoglicoside |
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A-84. Tetracycline works by blocking the________. Its side effects include?
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Acceptor site for incoming aminoacyl tRNA
Photosensitivity, promote the development of pseudotumor cerbri so don't use with Isotretinoin, avoid in kids <8yo, not for pregnant women |
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A-84. Name the "anti-folates" and what they tend to treat?
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Pyrimethamine, Trimethoprim
"Sulfa drugs," Dapsone Pneumocystis and T |
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A-84. What is Cytarabine primarily used for?
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Non-lymphocytic leukemia
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A-84. Fluoroquinolone (-oxacin drugs) inhibit bacterial topoisomerase II and are good for G+ and G- bugs. What are their contraindications?
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Don't use with Azoles, protease inhibitors and NNRTIs-can cause QT prolong and Torsades
Not for kis <16 Care in elderly - can cause tendon rupture |
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A-84. What does Rifampin treat?
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TB, leprosy, atypical mycobacterial infections
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A-84. What is the famous combo for ALL?
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POMP: Predinisone, Oncovin (vincristine), Methotrexate, Purimethol
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A-84. What are the SEs of Cyclophosphamide, Bleomycin, and Cisplatin?
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Cyclophosphamide: hemorrhagic cystitis
Bleomycin: pulmonary fibrosis Cisplatin: periph. neuropathy |
