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32 Cards in this Set
- Front
- Back
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What's the incubation period of:
-Hep A -Hep E -Hep D -Hep B -Hep C |
A = 2-6 wks
E = 3-6 wks D = 3-13 wks B = 8-24 wks C = 2-52 wks |
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Which hepatitis have onset thats
-Sudden -Insidious |
Acute = A, E, D.
Insidious = B, C. |
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How are Hepatitis A and E transmitted?
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-Food/water
-Fecal/oral |
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How are Hepatitis B, C, and D transmitted?
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-Parenteral
-Perinatal -Sexual |
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Which hepatitis types exhibit chronic states?
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B, C, and D.
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How would you diagnose Hepatitis due to alcoholic cirrhosis?
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AST high
ALT low |
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For which hepatitis viruses do immunizations exhist?
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-Hep A
-Hep B |
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What food is Hep A esp. associated with?
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Shellfish
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What 2 antibodies are used as serologic markers of HAV?
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1. Total Anti-HAV
2. IgM anti-HAV |
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what does Total Anti-HAV indicate?
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Immune status; it's a life-longer marker.
-Does NOT distinguish acute from past infection |
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What does IgM Anti-HAV indicate?
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Acute disease.Remains 6 months.
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What are the normal serologic markers on an Acute Viral Hepatitis panel?
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1. IgM Anti-HAV
2. HBsAg 3. IgM Anti-HBc 4. Anti-HCV |
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What's another name for Hep B?
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Serum hepatitis
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What is the danger of dying from hepatitis B in babies that recieve it perinatally?
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Low; but 95% chance of being a carrier.
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What shot is given to babies in case of Hep B transmisison?
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H-BIG.
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what is H-BIG?
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Anti-hepatitis B immunoglobulin; a passive antibody for immediate resistance to the organism.
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Who is at increased risk of developing chronic hep B?
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children under the age of 5.
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What is the 1st marker in Hep B?
When does it disappear? What does it infer? |
-HBsAG
-Gone with symptoms clearing -Infers infectivity |
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Which marker indicates ACUTE Hep B infeciton?
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Anti-HepB core IgM
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when does IgM Anti-HBc rise and fall?
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-Rises soon after HBsAg; falls soon after HbSAg, but TOTAL stays high.
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Which Hep B marker infers recovery and immunity?
-When does it appear? |
Anti-HBs; rises during convalescence.
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When does anti-HBe begin to replace HBe-Ag?
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When symptoms begin to disappear
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What can evaluating HBeAg and Anti-HBe levels do for evaluation of hepatitis B?
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Signal chronic infection; the antigen will remain for months to years, instead of only weeks.
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What 2 markers indicate chronic Hep B infections?
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-HBeAg present way too long
-HBsAg remains elevated instead of disappearing with symptoms. -NO ANTI-HBS APPEARS |
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what are 2 types of chronic HB?
What is the difference btwn them |
Chronic active
-Chronic persistant Difference: -Active does not seroconvert HBeAg to antibody. -Persistant does. |
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What are the 2 types of Hep D infection?
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-Co-infection with Hep B
-Superinfection |
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What is the deal with Hep D superinfection?
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-Occurs AFTER Hep B infection.
-Usually becomes chronic -Hi risk severe chronic liver disease. |
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What markers can we detect for Hep D in the lab?
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Anti-HDV Total
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what marker is useful in detecting hepatitis C?
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Anti-HCV
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how do we differentiate chronic infections from acute?
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Acute - normal ALT peak/decline
Chronic - crazy ALT levels |
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What is significant to remeber re: Anti-HCV?
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it is not protective.
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What 3 methods are used for supplemental testing for HC after the serological screen?
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-Recombinant immunoblot assay
-HCV RNA with PCR -Reverse Transcription PCR |
