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21 Cards in this Set
- Front
- Back
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333. Which of the following statements about the operon is INCORRECT?
A. The cyclic AMP-CAP complex binds to the operator site and allows transcription to begin B. The regulator site causes synthesis of repressor protein when RNA polymerase binds to the promoter site C. The inducer for transduction binds to the repressor protein and allows RNA polymerase to move along DNA D. Transcription factors can bind to DNA near promoter sites and enhance binding of RNA polymerase E. All of the above are correct |
The cyclic AMP-CAP complex binds to the operator site and allows transcription to begin
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334. RNA synthesis is terminated by
A. rho proteins B. base-pairing of RNA nucleotides to neighboring portions of the RNA molecule C. degradation of RNA polymerase D. All of the above are used to terminate transcription E. A and B, but not C |
A and B, but not C
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335. If the enzymes contained in splicosomes are inhibited, you would expect that
A. intron fragments would increase B. exon fragments would increase C. subsequenctly synthesized proteins would be non-functional D. repressor proteins would rapidly be made in order to save energy E. All of the above would be expected |
subsequenctly synthesized proteins would be non-functional
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336. Which of the following can be used by a cell to quickly increase the rate of protein synthesis?
A. Binding of cAMP-CAP to DNA B. Formation of polysomes C. Synthesize more ribosomes D. None of the above E. A and B, but not C |
A and B, but not C
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337. Which of the following molecules can act in a manner mediated by enhancers?
A. β-Estradiol B. Testosterone C. Vitamin D D. Progesterone E. All of the above |
All of the above
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338. Increased nuclear phosphatase activity will increase the rate of removal of phosphate groups. Which of the following is most likely to result following administration of a phosphatase activator?
A. Histones would tend to be more negatively charged B. Replication would be more difficult C. Transcription would be facilitated D. Only histones H1 and H2A would be affected E. Supercoiling would be enhanced |
Replication would be more difficult
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339. Which of the following would tend to inhibit expression of a gene?
A. Presence of an inducer. B. Activation of a protein like Catabolite Activator Protein. C. Addition of actinomycin D. Signal binding to repressor protein E. All of the above would tend to decrease transcription. |
Addition of actinomycin
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340. Down regulation
A. Is a way for ducks to regulate body temperature B. Refers to the ability of a product to inhibit the enzyme that produced it C. Is a process wherein fewer receptors are synthesized when signal has been plentiful D. Increases the sensitivity of a cell to a signal E. Decreases the Km of an enzyme |
Is a process wherein fewer receptors are synthesized when signal has been plentiful
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341. Cell differentiation is regulated by
A. Master gene regulatory proteins B. Alternative splicing of hnRNA C. mRNA transport across the nuclear membrane D. mRNA degradation rates E. All of the above |
All of the above
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342. Premature termination codes
A. Are palindromic sequences followed by a poly-U "tail" B. Are present only in the nuclear DNA of cells which will not express the protein C. Require the presence of a stabilizing protein for full transcription D. Result from intron ambiguity E. Are activated when phosphorylated |
Require the presence of a stabilizing protein for full transcription
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343. RNA leaving the nucleus to be translated does so in the form of
A. mRNA B. hnRNA C. tRNA D. Ribonucleoprotein particle E. Combinatorial gene |
Ribonucleoprotein particle
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344. Rapid ferritin synthesis in response to an increase in cytosolic iron makes use of which regulatory process?
A. Removal of translation repressor protein from existing mRNA B. Binding of transcription enhancer proteins to DNA C. Enhanced transport of existing mRNA from the nucleus to the cytosol D. Alternative splicing promoted by intron ambiguity E. Transcription attenuation |
Removal of translation repressor protein from existing mRNA
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345. mRNA stability
A. Is fixed, and longer in prokaryotes than eukaryotes B. Is fixed, and longer in eukaryotes than prokaryotes C. Is variable, and longer in eukaryotes than prokaryotes D. Is decreased by the presence of steroid hormones in eukaryotes E. Is decreased by the presence of steroid hormones in prokaryotes |
Is variable, and longer in eukaryotes than prokaryotes
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346. Which of the following is NOT a part of the operon?
A. Gene B. Operator site C. Regulator site D. Promoter site E. All of the above are part of the operon |
All of the above are part of the operon
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347. You would find a Pribnow Box
A. At the Promoter site B. As the primary catalytic unit of DNA polymerase C. In the transcript unit of a gene D. At the Operator site E. At the Regulator site |
At the Promoter site
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348. The Operator site of an operon
A. Is recognized by the sigma subunit of RNA polymerase B. Is the location for binding of positive transcription factors C. Is the location where repressor proteins bind D. Contains the code which will be transcribed E. Directly binds to the inducer |
Is the location where repressor proteins bind
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349. Differential expression of what percent of total protein is required for cell differentiation?
A. <1% B. ~10% C. ~50% D. ~90% E. >99% |
<1%
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350. Cell differentiation is under the control of
A. Gene regulatory proteins B. Master gene regulatory proteins C. Inducers D. Puromycin E. Testosterone or estrogen |
Master gene regulatory proteins
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351. Which of the following is NOT a post-transcriptional mechanism for regulating gene expression?
A. Premature termination codes B. Alternative splicing C. Transport across the nuclear envelope D. Presence of translation repressor proteins E. Alteration of mRNA catabolism rate |
Premature termination codes
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352. The presence of two palindromic sequences in a single gene
A. Is never observed B. Is used to produce the normal transcript C. Can lead to premature termination of a transcript D. Requires the presence of single stranded binding proteins E. Leads to intron ambiguity |
Can lead to premature termination of a transcript
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353. Which of the following addresses the term “degenerate” nature of the DNA code?
A. One tRNA can bind two or more different amino acids B. The absence of exonuclease activity in RNA polymerases results in many mistakes during transcription C. There are multiple codons for one amino acid D. The protein produced by translation of an mRNA molecule depends on the type of ribosome involved in translation E. About 10% of all DNA code is changed during each replication cycle |
There are multiple codons for one amino acid
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