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16 Cards in this Set
- Front
- Back
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What is the pathology of Microsopic polyangitis?
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Necrotizing vasculitis incolving lungs/kidneys/skin
Pauci-immune (minimal evidence of hypersensitivity) glomerulonephritis and palpable purpura |
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What is diagnostic of Microsopic polyangitis?
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p-ANCA
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How do you treat Microsopic polyangitis?
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Corticosteroids, Cyclophosphamide
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What are some symptoms of Wegener's granulomatosis?
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Respiratory tract:
Perforation of nasal septum Chronic sinusitis Otitis media Mastoiditis |
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What is diagnostic of Wegener's Granulomatosis in the kidneys?
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Red cell casts
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What is the triad of Wegener's Granulomatosis?
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Focal necrotizing vasculitis
Necrotizing granulomas in the lung and upper airway Necrotizing glomerulonephritis |
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What is diagnostic of Wegener's Granulomatosis?
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c-ANCA
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How do you treat Wegener's Granulomatosis?
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Cyclophosphamide, corticosteroids
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What are the 4 symptoms of Churg-Strauss syndrome?
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Asthma, sinusitis, palpable purpura, peripheral neuropathy
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What is the pathology of Churg-Strauss syndrome?
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Granulomatous necrotizing vasculitis with eosinophilia
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What is diagnostic of Churg-Strauss syndrome?
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p-ANCA, elevated IgE
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What is the most common childhood systemic vasculitis?
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Henoch-Schonlein purpura
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What does Henloch-Schonlein purpura often follow?
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URI
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What is the classic triad of Henloch-Schonlein purpura?
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Purpura of buttocks/legs
Arthralgia (usually in knees) Abdominal pain |
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What is the pathology of Sturge-Weber disease?
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Congenital vascular disorder that affects capillary sized blood vessels
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What is the manifestation of Sturge-Weber disease?
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Port-wine stain on face in the opthalmic division of trigeminal nerve
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