7 (Blood Bank A)

Front 1

First off, donor should be in good health, but

what ages are acceptable for donating blood?

Back 1

Under 17 years requires adult consent.

No general upper age limit.

Front 2

What are the weight restrictions for blood donations?

Back 2

No less than 50kg (110lb)

Unexplained weight loss of 10lb is reason for deferral

Front 3

What are the temperature restrictions for blood donation?

Back 3

Temperature must not exceed 37.5C (99.5F)

Front 4

What are the pulse and blood pressure restrictions for blood donation?

Back 4

Pulse: 50 -100 bpm

Blood Pressure:

(systolic) Not higher than 180mmHg

(diastolic) Not higher than 100mmHg

Front 5

What are the hematocrit and hemoglobin levels for blood donation?

Back 5

Hct: 38%

Hgb: 12.5g/dL

Front 6

How long until a person can donate again after:

Blood donation -

Hemapheresis -

Back 6

Blood donation - 8 weeks

Hemapheresis - 48 hours

Front 7

These are reasons for ______ deferral of donors:

-hepatitis after 11yrs old

-present/past infection of Hepa C, HIV, HTLV I/II

-history of Crutzfeldt-Jakob disease

-positive HBsAg

-repeated positive anti-HBC

Back 7

permanent

Front 8

These are reasons for ______ deferral of donors:

-narcotic or alcohol addiction

-donated and recipient developed post transfusion hepa

-history of Chagas disease, babesiosis or malaria

-chemotherapy medication or psoriasis

Back 8

permanent

Front 9

These are reasons for a ______ deferral of donors:

- Visitor/Immigrant from area of endemic for malaria

- had malaria and is now asymptomatic

Back 9

3 year

Front 10

These are reasons for a ___ deferral of donors:

- hepa B immune globulin admin.

- after rabies vaccination

- rape victims or workers w/ exposure to blood products

- incarceration for more than 72hrs

- history, treatment or (+) screening test for gonorrhea or syphilis

- travel to malaria endemic places

Back 10

1 year

Front 11

What are some reasons for a 2 month deferral of donors?

Back 11

Recent blood donation

Front 12

What are some reasons for a 6 week deferral of donors?

Back 12

After delivery of a baby

Front 13

These are reasons for a _____ deferral of donors:

- German measles (rubella) vaccine

- After treatment of isotretinoin

- After treatment of finasteride (benign prostatic hyperplasia)

Back 13

1 month

Front 14

What are some reasons for a 48 hour deferral of donors?

Back 14

After hemapheresis

Front 15

The withdrawal of whole blood from a donor, removing selected components and re-infusion of the remainder back to donor

Back 15

hemapheresis/apheresis

Front 16

In hemapheresis/apheresis what is the maximum amount of plasma that can be removed at one time?

Back 16

500mL

Front 17

Used to reconstruct bone marrow post-chemotherapy or to replace abnormal marrow cells w/normal ones.

Back 17

Hematopoietic progenitor and stem cell collection

Found in:

Bone marrow

Umbilical cord

Peripheral blood

Front 18

Type of blood given cases of severe shock and in need of RBC's for oxygen

Back 18

whole blood

Front 19

In RBCs, ____ % hct means insufficient plasma removal

Back 19

80%

Front 20

1 unit of packed red cells (RBC) raises ____ of hemoglobin or ____ of hematocrit

Back 20

1g hb or 3% hct

Front 21

Type of cells in which:

- Plasma is removed by successive saline washes.

- Prevents allergic response and anaphylactic shock in IgAdeficient patients w/anti-IgA

Back 21

Washed Red Cells


- Expires 24hrs after seal of original unit is broken

Front 22

Type of cells in which:

- 85% of red cells are retained- Final WBC ct. is <5 x 10⁶ to prevent febrile non-hemolytic reactions

- Used primarily for patients w/repeated non-hemolytic reactions due

Back 22

Leukocyte reduced red cells

Front 23

What are the methods of preparation for Leukocyte reduced red cells?

Back 23

Filters – removes leukocytes

Washed/Frozen-thawed RBCs

Front 24

Type of cells in which:

- Cells are protected from ultra-low temp. by cryoprotective agent (glycerol)

- 80% of original red cells must be recovered

- Used for storing autologous or “rare” units

Back 24

Frozen cells

Front 25

Frozen cells must be thawed at _____C and glycerol is removed prior to transfusion

Back 25

37C

Front 26

Frozen cells are stored at what temperature?

Back 26

-65C or colder

Front 27

Frozen cells must be stored at _____C for 24hrs after deglycerolizing

Back 27

1-6C

Front 28

Type of cells:

- Which are prepared by separating cells and plasma via centri and then freezing plasma w/in 8hrs of collection

- Must be ABO compatible w/recipient cells

Back 28

FFP

Front 29

What temp is FFP stored and how long until it expires?

Back 29

FFP is stored at -18C or colder

and expires 1yr after freezing

Front 30

What temp is FFP thawed and how long until it expires?

Back 30

FFP is thawed between 30-37C and expires in 24hrs if kept at 1-6C

Front 31

FFP is used for Factor ___ deficiency and other congenital deficiencies.

Back 31

Factor XI

Front 32

Type of cell:
The cold insoluble portion of plasma processed from FFP

Back 32

Cryoprecipitate

Front 33

Cryoprecipitate must contain at least ____mg of fibrinogen and 80 IU/bag of Factor _____

Back 33

150mg of fibrinogen

80 IU of factor VIII

Front 34

Cryoprecipitate must be frozen within _____ of collection of whole blood unit

Back 34

8hrs

Front 35

If cryoprecipitate is thawed after collecting from whole blood unit, it must be refrozen within _____

Back 35

1 hour.

(What temp is cryo thawed out from whole blood collection?)

Hint 35

1-6C

Front 36

You must transfuse cryo within ____ after thawing.

Back 36

6hrs

(What temp is cryo thawed before transfusion?)

Hint 36

30-37C

Front 37

Once FFP has thawed, what temp do you store it?

Back 37

1-6C

Front 38

Used for:

- Factor XIII and fibrinogen

- Fibrin seal

Back 38

Cryoprecipitate

Front 39

Factor ____ treats hemophilia A

Back 39

Factor VIII

Front 40

Factor ____ treats Christmas Disease and inhibits Factor VIII

Back 40

Factor IX

Front 41

To prepare platelets from whole blood it must undergo a light and then heavy spin. Why?

Back 41

Light spin removes red cells

Heavy spin is to spin down platelets and WBCs

Front 42

What makes up platelet concentrate?

Back 42

Platelets, and WBCs

Front 43

Given to patients with severe thrombocytopenia and platelet dysfunction

Back 43

platelets

Front 44

How do you collect platelets?

Back 44

1. light spin then heavy spin

2. supernatant is put in a bag as FFP

3. remaining platelets and WBC make up platelet concentrate

Front 45

1 unit of platelet concentrate raises the platelet ct up to _____

Back 45

5,000 - 10,000 /uL

Front 46

How should you store platelets?

Back 46

Continuously rotating at 20-24C

Front 47

What is the pH of platelets and describe its ABO compatibility.

Back 47

pH >6.2

Only one ABO type/pool

(Expires 4 hours)

Front 48

Usually obtained by apheresis and is used for neutropenic patients w/documented sepsis who have not responded to antibiotics

Back 48

Granulocytes

(stored at 20-24C)

Front 49

Prevents graft (donor lymphs)

vs.

Host disease (recipient disease)

by inactivating donor lymphs

Back 49

Irradiated blood and components

Front 50

Irradiated blood and components are recommended for what kind of patients?

Back 50

Immuno-suppressed

Immuno-comprised

Recipients of units from blood relatives

Recipients who have undergone bone marrow transplants

Front 51

Temp. for Transporting Blood & Components:

Red cells -

Platelets & Granulocytes -

Back 51

Red cells: 1-10C

Platelets & Granulocytes: 20 - 24C

Front 52

In the open system, what are the expiration of pooled components?

Platelets:

Cryo:

Back 52

Platelets: 4 hours

Cryo: 4 hours

Front 53

A unit of blood cannot be returned or re-issued if:

Back 53

It is stored >10C for 15-30mins

or if seal is disturbed