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8 Cards in this Set

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Most common tumors:

Children?
Children = meduloblastomas

Adult = Astrocytomas ... can progress to secondary glioblastomas (collect mutations...clonal selection)
Meningioma cell origin.

Pathology of meningioma.
Cells lining arachnoid villa. Great prognosis if treated early.

Path = whirls
Sites of meningioma growth
falx cerebri, foramen magnum, sphenoid ridge, olfactory groove (PATIENTS WITH SMELL DEFECTS - CN II, III defects?)
Location of tumors presenting w/ seizures?
Temporal lobe involvement. Low grade tumors (better prognosis) = higher epilepsy rates.
Edematous white matter
Pass through tight junctions. Increase in proteinacious edema.
Causes of ring-enhancing lesions
PRIMARILY METASTASES (b/c highest prevalence). Can be abscesses, primary tumors, hematomas, MS
Tumor Grading Scale
I (Low = good): Cellularity
II: Pleiomorphism
III: Mitoses
IV: (BAD) Necrosis
V: (BAD) Angiogenesis
Glioblastomas
BAD BAD!