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16 Cards in this Set

  • Front
  • Back

A patient is started on terazosin therapy. Counseling points should include the following: (Select ALL that apply.)


Answer


AWhen you move from sitting to standing up, hold onto the bed rail or table until you feel steady.


BTaking pseudoephedrine can help limit the dizziness.


CIt is best to begin taking the medication at bedtime.


DThe dose is started low and will be increased when you get used to the side effects.


EThis agent should be taken three times daily.


AWhen you move from sitting to standing up, hold onto the bed rail or table until you feel steady.



CIt is best to begin taking the medication at bedtime.


DThe dose is started low and will be increased when you get used to the side effects.

A patient gave the pharmacist a prescription for dutasteride. Which of the following is the correct brand name for dutasteride?


Answer


AFlonase


BFlovent


CFlomax


DAvodart


ERapaflo

DAvodart

Susan is a pharmacist who dropped a tablet of finasteride on the floor. While looking for it, she stepped on it. Susan does not pick up the tablet with her hands. She carefully uses paper to scoop up the pieces and disposes of the waste. Susan is cautious in handling this drug for the following reason:


Answer


AShe is aware that dust from this drug has been implicated in causing breathing difficulty, with bronchoconstriction.


BShe could develop a blistery rash.


CShe is aware that if she is pregnant, a male fetus could be harmed if she touches the medicine.


DShe is afraid of the drug causing breast cancer.


EShe is afraid of the drug causing endometrial cancer.

CShe is aware that if she is pregnant, a male fetus could be harmed if she touches the medicine.

If a drug used by older males contributes to sexual dysfunction, it will affect the adherence as many men have problems with sexual function as they age and would not wish to worsen or cause this condition. What is the effect of the alpha blockers on sexual function? (Select ALL that apply.)


Answer


AAlpha blockers typically worsen erectile dysfunction.


BSilodosin can cause retrograde ejaculation.


CTypically, the alpha blockers do not cause sexual dysfunction.


DSilodosin can cause an orgasm with little or no semen.


EAlpha blockers can cause priapsim.

BSilodosin can cause retrograde ejaculation.


CTypically, the alpha blockers do not cause sexual dysfunction.


DSilodosin can cause an orgasm with little or no semen.


EAlpha blockers can cause priapsim.

If a drug decreases PSA and shrinks the prostate, it could mask prostate cancer. Which of the following drugs decrease PSA and shrink the prostate?


Answer


ATamsulosin


BSilodosin


CAlfuzosin


DFinasteride


EDoxazosin


DFinasteride

An elderly gentleman with benign prostatic hyperplasia (BPH) has gone to see the physician and presents to the pharmacy with a prescription for finasteride. Choose the most appropriate counseling statements concerning sexual dysfunction and the 5 alpha-reductase inhibitors: (Select ALL that apply.)


Answer


AThese drugs often cause impotence.


BA small number of men (under 10%) will have problems with sexual function on these drugs, but in most cases it does not remain a problem.


CIf you have any concerns, please discuss them with your healthcare provider.


DThe incidence of impotence can be decreased by taking decongestants.


EThe incidence of impotence can be decreased by taking antihistamines.


BA small number of men (under 10%) will have problems with sexual function on these drugs, but in most cases it does not remain a problem.


CIf you have any concerns, please discuss them with your healthcare provider.

An elderly gentleman with benign prostatic hyperplasia (BPH) has gone to see the physician and presents to the pharmacy with a prescription for finasteride. He had already been using tamsulosin for two months but states it has not helped enough. Choose the correct statement regarding finasteride: (Select ALL that apply.)


Answer


AFinasteride blocks the 5-alpha reductase enzyme that converts testosterone to DHT.


BFinasteride is an alpha-1A selective receptor blocker.


CFinasteride starts working in 1-2 days.


DFinasteride is Pregnancy Category X.


EFinasteride and tamsulosin should not be used together.


AFinasteride blocks the 5-alpha reductase enzyme that converts testosterone to DHT.




DFinasteride is Pregnancy Category X.

A patient presents with symptoms of prostate enlargement. Prior to initiating treatment, the physician wishes to rule out prostate cancer. Which tests could be used to check for the possibility of prostate cancer? (Select ALL that apply.)


Answer


ACreatine Phosphokinase (CPK)


BProstate specific antigen (PSA)


CTURP


DFOBT


EDigital rectal exam (DRE)

BProstate specific antigen (PSA)




EDigital rectal exam (DRE)

Tadalafil has been approved for use in BPH. Which of the following statement/s are correct? (Select ALL that apply.)


Answer


AUse caution due to dizziness, possible drop in blood pressure and headache.


BAt this low dose the risk of vision or hearing loss is not relevant; these conditions occur at the higher end of the dosing range only and counseling on these possible adverse effects is not required.


CThe brand name is Levitra.


DBlurred vision, difficulty distinguishing between blue and green, or haziness around lights, which can make driving at night difficult.


EIf the man uses this drug for BPH, he will still need to take an additional dose for erectile dysfunction.

AUse caution due to dizziness, possible drop in blood pressure and headache.




DBlurred vision, difficulty distinguishing between blue and green, or haziness around lights, which can make driving at night difficult.

Jerry uses tadalafil for erectile dysfunction. His other medications are lisinopril-HCT and pravastatin. Jerry has gone to the doctor and answered questions regarding how bothersome his BPH symptoms are currently. Based on his score, the physician decided to start tamsulosin (Flomax). Should the pharmacist dispense the alpha blocker to this patient?


Answer


AYes, but he should receive 0.8 mg daily to start.


BYes, but caution is advised about additive hypotension and dizziness.


CNo; he is using a PDE-5 inhibitor.


DNo, he has hypertension.


ENo, he should use a non-selective alpha blocker first-line.

BYes, but caution is advised about additive hypotension and dizziness.

Jerry is a 75 year-old male who is having difficulty with urination. He reports that he cannot "empty" his bladder when he uses the bathroom, and the urine comes out "dribbling." The urologist ruled-out prostate cancer and wrote Jerry a prescription for tamsulosin 4 mg daily. Jerry has no other known medical conditions. Choose the correct statements: (SelectALL that apply.)


Answer


ATamsulosin blocks alpha receptors in prostate tissue.


BThe dose of tamsulosin is correct.


CThe brand name of tamsulosin is Flomax.


DTamsulosin commonly causes erectile dysfunction.


EDizziness and orthostasis occur more commonly with tamsulosin than doxazosin.

ATamsulosin blocks alpha receptors in prostate tissue.



CThe brand name of tamsulosin is Flomax.

An elderly gentleman enters the pharmacy. He is using tamsulosin, dutasteride, atenolol and candesartan. He has a bad cold. He sounds "nasal" because he is congested. He is asking for advice on a cold product. Choose the agent least likely to worsen the BPH symptoms:


Answer


AOxymetazoline nasal spray, taken BID for not more than three days


BPseudoephedrine


CDiphenhydramine


DA combination product with phenylephrine, chlorpheniramine and acetaminophen


EA combination product with phenylephrine, diphenhydramine and ibuprofen

AOxymetazoline nasal spray, taken BID for not more than three days

A patient with prostate enlargement was prescribed doxazosin. He experienced dizziness and found that when he went from sitting to standing, or lying down to sitting, he felt dizzy and his head "swooned." The physician is considering switching him to tamsulosin. Choose the correct statement:


Answer


AThe dizziness would be about the same with tamsulosin.


BIf the doctor wished to avoid the dizziness, he should switch the patient to terazosin.


CA better option would be to start pseudoephedrine therapy with the doxazosin.


DA drug with the same mechanism of action as doxazosin but with less dizziness is finasteride.


ETamsulosin is an alpha 1a-selective blocker and causes less dizziness and orthostasis than doxazosin.

ETamsulosin is an alpha 1a-selective blocker and causes less dizziness and orthostasis than doxazosin.

A patient gave the pharmacist a prescription for finasteride 5 mg one tablet by mouth each morning #30. Which of the following is the correct brand name for finasteride when used for prostate enlargement?


Answer


APropecia


BProscar


CJalyn


DAvodart


ERapaflo

BProscar

A patient is beginning therapy for BPH with tamsulosin. When should he take the medicine?


Answer


AThirty minutes after the same meal each day


BOne hour before breakfast on an empty stomach


CAt bedtime


DWith lunch


EWith a light snack in the mid-afternoon

AThirty minutes after the same meal each day

Alfuzosin (Uroxatral) and silodosin (Rapaflo) are newer alpha-1A selective blockers, in the same class as tamsulosin. These drugs are not likely to become as popular as tamsulosin because they have the following safety consideration:


Answer


AAlfuzosin and silodosin are CYP 450 3A4 substrates; the use of 3A4 inhibitors will decrease the alpha blocker's concentration and effectiveness.


BAlfuzosin causes hair loss.


CAlfuzosin prolongs the QT interval and can be dangerous in patients with cardiac conditions or those using other QT-prolongating drugs.


DAlfuzosin must be taken at night.


ESilodosin must be taken at night.

CAlfuzosin prolongs the QT interval and can be dangerous in patients with cardiac conditions or those using other QT-prolongating drugs.