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19 Cards in this Set
- Front
- Back
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What are the main features seen in ITP?
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-Recent viral URI
-Low platelets -Petechiae/purpuric rash |
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What is the test your should order for ITP?
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CBC - look at a PBS for immature white cells and RBC morphology
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If you saw schistocytes what would you think of?
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DIC
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If you saw immature leukocytes what might you consider?
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Leukemia BM infiltration
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If a patient had nephropathy and low platelets what should you consider?
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Hemolytic uremic syndrome
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What causes HUS?
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Ecolo 0157H7
Salmonella Shigella |
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What vasculitide may have thrombocytopenia?
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HSP - Henoch schonlein purpura
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What are the 4 systems involved in HSP?
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Skin - petechia/purpura rash
GI - abdom pain, blood in stool Joints - pain Kidney - nephritis/nephrosis |
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What other GI condition is associated with HSP?
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INTUSSUSCEPTION
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Why is there thrombocytopenia in ITP?
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Circulating Anti-GP2b/3a causes increased platelet destruction
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In what age group is ITP usually?
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2-5 yr
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What test should be done if there are immature WBCs/RBC morphology, or organomegaly/adenopathy?
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Bone marrow eval
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What will BM aspirate show in ITP?
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Increased megs
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By what time frame will most ITP patients have resolution of sx?
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6 months
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What is the most SERIOUS complication of ITP?
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Intracranial hemorrhage
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Should ITP be treated?
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Not sure
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What is treatment for ITP?
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-IVIG daily for 1-2 days
-Systemic corticosteroids 2-3wks or -IV anti-D therapy |
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When should you give a platelet transfusion for ITP?
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Only if they have life-thx bleeding
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What vaccine should be used cautiously in ITP patients?
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MMR - may cause thrombocytopenia
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