5.26 Qbank

Front 1

1. Why would bordatella pertusis, a bacteria, stimulate lymphocye recruitment?

2. Other than renal cell carcinoma, what other cancers have EPO as a paraneoplastic syndrome? (2)

3. What first component to the DIC cascase?

Back 1

1. exotoxin stimulates lymphocytes to respond

2. hemangioma, hepatocellular carcinoma

3. TF exposure

Front 2

1. Why does bordatella stimulate hypoglycemia?

2. Why does Acetazolamide cause NH3 toxicity?

3. For cryin' out loud, what does omeprazole work on? What has a compensatory increase when you use it?

Back 2

1. exotoxin stimulates the islets of langerhaans

2. Becaues NH4+ can sub for H+ on Na+/H+. AC blocks this and NH3 builds up (see sheet)

3. Works on K/H+ pump; compensatory increase in gastrin

Front 3

1. Not all H2 receptor antagonists block CytP450 but one does. Which one is it?

2. DOC for iron toxicity?

3. Which cells are CD14+?

Back 3

1. Cimetidine

2. Deferoxime

3. Macrophages

Front 4

1. DOC for copper toxicity?

2. What does a deficiency in any glycolytic enzyme have the potential to result in?

3. Which Cells are CD56+?

Back 4

1. Penacillaminase

2. hemolytic anemia

3. NK cells

Front 5

1. DOC for Lead toxicity?

2. What is the function of the Cori cycle?

3. Which cell type will be MOST PROMINENT in a +PPD skin test area?

Back 5

1. EDTA (or succimer)

2. Takes lactate building up in the muscles and sends it to the liver to make new glucose (gluconeogenesis)

3. Macrophage (antigen presenting cells)

Front 6

1. DOC for mercury toxicity?

2. What is the triad for Wiskott Aldridge Syndrome?

3. Where is functional dead space more likely to be located?

Back 6

1. Dimercaperol

2. wasTER: Thrombocytopenia, Ezcema, Recurrent URIs

3. Lung apices

Front 7

1. Compare the venous area supplied by the great saphenous vein and the short saphenous vein? Where do each drain lymphatically?

2. What is the function of Ki-67 staining?

3. How is arterial O2 saturation curve affected by altitude?

Back 7

1. great saph: medial side of leg/drains to inguinal nodes; short saph: lateral side of leg/drains to popliteal nodes

2. Gives information about RATE of proliferation

3. shifts curve to the right so lower O2 sat (more being unloaded)

Front 8

1. What is the most specific sign of CHF?

2. How is renin output effected by renal failure?

3. What are the two causes of chronic gastritis?

Back 8

1. S3

2. Despite the lower filtration, renin will still be decreased

3. Autoimmune, Bacterial (H. Pylori)

Front 9

1. What is the function of the nitroblue tetrazolium test?

2. What is the molecular defect in Bruton's Agammaglobinemia?

3. What is the RecA bacterial gene responsible for?

Back 9

1. looks for reactive O2 species to r/o NADPH deficiency from Chronic Granulomatous Disease

2. Bruton's tyrosine kinase (BTK)

3. Homologous recombination

Front 10

1. What is the difference between an F+ and an Hfr bacterial cell?

2. The Ret oncogene is associated with what conditions?

3. Diagnose: 60 year with ripping pain radiating to the back that eventually moves towards the flanks?

Back 10

1. F+ has conjugative episome, Hfr has integrated episome into its chromosome

2. MEN IIa,IIb

3. AAA involving renal arteries

Front 11

1. What conditions cause expansion of the calvarium on XRay? (2)

2. How does high blood pressure lead to a decrease in numerical arterial density?

3. Compare the conditions that are most likely to predisposed a person to an aneurysm and a dissection?

Back 11

1. thalassemias and sickle cell

2. pressure moves away dilatory metabolites causing eventually permanent closure.

3. aneurysm: atherosclerosis, dissection: hypertension

Front 12

1. What are Downey cells and what are they indicative of?

2. What are SYMPATHETIC cholinergic neurons mostly responsible for?

3. What are two MOOD disorders?

Back 12

1. Atypical B lymphocytes seen in EBV infection

2. sweating

3. bipolar and unipolar depression

Front 13

1. Describe the four types of follicles and what type of oocyte (XN?) are present in them?

2. What structure could impinge on another stucture causing vertical gaze paralysis?

Back 13

1. all have a primary oocyte (4N) primordial follicle: one layer cubdoidal w/o antrum;
primary follicle: multiple layer cuboidal w/o antrum;
secondary follicle: multiple layer cuboidal w/ small antrum;
graffian follicle: large antrum, pushed out to side

2. pineal gland on the superior colliculus

Front 14

1. What CNs arise from the cerebellopontine angle?

2. How does vancomycin resistant staph aureus acquire resistance genes?

Back 14

1. CN VII/VIII

2. plasma conjugation

Front 15

1. How does strep pneumo aquire pencillin resistance genes?

2. What is the inciting event for pre-eclampsia?

Back 15

1. transformation

2. placental ischemia

Front 16

1. How does MRSA acquire its resistance genes?

2. What is HELLP syndrome?

Back 16

1. general (lytic) transduction

2. associated with pre-eclampsia: hemolysis, elevated LFTs, low platelets