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12 Cards in this Set
- Front
- Back
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What doe polycythemia mean?
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increased RBCs only
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what does polycythemia vera mean?
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increased ALL cells - panmyelosis
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what are 2 forms of polycythemia?
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1. Relative
2. Absolute |
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what is relative polycythemia?
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a relative increased in RBCs secondary to an absolute decreased blood volume.
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what causes relative polycyth?
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Dehydration or stress erythrocytosis.
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what is absolute erythrocytosis?
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a true increase in RBC
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What is secondary polycyth stimulated by?
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EPO stimulating erythroid precursors.
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What is the disease mechanism that occurs in 2ndary polycyth?
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O2 supply to kidneys decreased; causes EPO production to increase, thus RBC production.
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Why is there O2 deficiency in the first place?
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1. High altitude
2. heart/lung problems 3. decr. blood volume, [Hb], O2 affinity 2. Disease state |
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what 3 Hb abnormalities decrease its O2 affinity?
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1. Hb Chesapeake/Little Rock
2. Methemoglobin 3. Carboxyhb |
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which 5 disease states can cause o2 hypoxia?
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1. renal ischemia
2. renal artery stenosis 3. renal cysts 4. hydronephrosis 5. kidney/liver tumors |
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In general, what kind of problem is Primary Polycythemia?
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a myeloproliferative disorder involving all cell lines.
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