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24 Cards in this Set
- Front
- Back
Chicken Pox Agent
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Varicella zoster virus
Member of the herpes family Medium sized, enveloped dsDNA |
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Chicken Pox Symptoms
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Skin rash on head, face, and mouth
Sequella - reactivation as shingles Reye's Syndrome - vomiting and coma, liver and brain damage |
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Chicken Pox Pathogenesis
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Enters thru respiratory route
Moves to skin thru blood stream Infect and lyse cells Can remain in nerves Decline in cell mediated immunity yields shingles |
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Chicken Pox Epidemiology
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Spread thru resp. droplets and skin lesions
Incidence increases in winter and spring 2 weeks incubation, infective 1-2 days before rash until blisters scab over |
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Chicken Pox Prev/Treat
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Vaccine or antibody therapy for immunocompromised
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Measles Agent
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Rubeola virus, paramyxovirus family
Pleomorphic, medium sized, enveloped ssRNA 2 envelop projections. One for attachment, one for membrane fusion |
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Chicken Pox Symptoms
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Fever, runny nose, etc.
Fine rash spreading from forehead Disappears in 1 week Secondary infections - pneumonia and earaches. Encephalitis and subacute sclerosing panencephalitis in sever cases |
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Chicken Pox Pathogenesis
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Infects thru respiratory route
Replicates in epithelium Spreads to lymph nodes then to rest of body Mucus membranes covered with white spots - Koplik spots Rash due to replication and immune response |
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Chicken Pox Epidemiology
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Humans are only natural host
Spread thru droplets Rare in US but outbreaks still occur |
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Chicken Pox Prev/Treat
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Vaccine
No antivirals |
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German Measles
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Rubella virus
Togavirus family Smal, enveloped, ssRNA |
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Chicken Pox Symptoms
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Slight fever and cold symptoms
Enlarged lymph nodes behind ears and back of neck Faint light pink spot rash on face Adults complain of joint pain Usually last about 3 days |
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Chicken Pox Pathogenesis
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Enters thru respiratory route
Multiplies in nasopharanx then enters blood stream - viremia Transported to tissues Antibody-antigen complex causes rash and joint pain |
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Chicken Pox Epidemiology
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Humans are only natural host
Highly infectious but less than rubeola 40% are asymptomatic Infectious for a week before and after rash |
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Chicken Pox Prev/Treat
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Attenuated virus vaccine, given at 12 months then booster at 4-6 years
Dangerous to pregnant women |
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Fifth Disease
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Parvovirus B-19
Small, nonenveloped, ssDNA Infects certain bone marrow Can cause aplastic crisis |
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Roseola
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Herpes virus type 6
Common in young children Abrupt, high fever followed by rash, sometimes covulsions No vaccine, treatment to reduce fever |
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Warts Agent
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Papillomavirus
Papovirus family SMall, nonenveloped, dsDNA Can survive on fomites |
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Warts Pathogenesis
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Infects deeper cells of epidermis
Reproduces inside cell nucleus Infected cell grows abnormally 2-18 month incubation |
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Wart Treatment
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Killing abnormal cells
Freezing, cauterizing, surgical removal |
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Superficial Cutaneous Mycoses Agent
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Epidermophyton
Microsporum Trichophyton Known collectively as dermatophytes |
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Superficial Cutaneous Mycoses Symptoms
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Itching
Odor Rash Some show no symptoms |
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Superficial Cutaneous Mycoses Pathogenesis
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Skin is normally resistant
Excess moisture allows invasion of keratinized tissue Keratinase - metabolizes keratin Difuse to dermal layer and evoke immune response |
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Superficial Cutaneous Mycoses Prev/Treat
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Attention to cleanliness
Keeping dry OTC medications |