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24 Cards in this Set

  • Front
  • Back
Chicken Pox Agent
Varicella zoster virus
Member of the herpes family
Medium sized, enveloped dsDNA
Chicken Pox Symptoms
Skin rash on head, face, and mouth
Sequella - reactivation as shingles
Reye's Syndrome - vomiting and coma, liver and brain damage
Chicken Pox Pathogenesis
Enters thru respiratory route
Moves to skin thru blood stream
Infect and lyse cells
Can remain in nerves
Decline in cell mediated immunity yields shingles
Chicken Pox Epidemiology
Spread thru resp. droplets and skin lesions
Incidence increases in winter and spring
2 weeks incubation, infective 1-2 days before rash until blisters scab over
Chicken Pox Prev/Treat
Vaccine or antibody therapy for immunocompromised
Measles Agent
Rubeola virus, paramyxovirus family
Pleomorphic, medium sized, enveloped ssRNA
2 envelop projections. One for attachment, one for membrane fusion
Chicken Pox Symptoms
Fever, runny nose, etc.
Fine rash spreading from forehead
Disappears in 1 week
Secondary infections - pneumonia and earaches. Encephalitis and subacute sclerosing panencephalitis in sever cases
Chicken Pox Pathogenesis
Infects thru respiratory route
Replicates in epithelium
Spreads to lymph nodes then to rest of body
Mucus membranes covered with white spots - Koplik spots
Rash due to replication and immune response
Chicken Pox Epidemiology
Humans are only natural host
Spread thru droplets
Rare in US but outbreaks still occur
Chicken Pox Prev/Treat
Vaccine
No antivirals
German Measles
Rubella virus
Togavirus family
Smal, enveloped, ssRNA
Chicken Pox Symptoms
Slight fever and cold symptoms
Enlarged lymph nodes behind ears and back of neck
Faint light pink spot rash on face
Adults complain of joint pain
Usually last about 3 days
Chicken Pox Pathogenesis
Enters thru respiratory route
Multiplies in nasopharanx then enters blood stream - viremia
Transported to tissues
Antibody-antigen complex causes rash and joint pain
Chicken Pox Epidemiology
Humans are only natural host
Highly infectious but less than rubeola
40% are asymptomatic
Infectious for a week before and after rash
Chicken Pox Prev/Treat
Attenuated virus vaccine, given at 12 months then booster at 4-6 years
Dangerous to pregnant women
Fifth Disease
Parvovirus B-19
Small, nonenveloped, ssDNA
Infects certain bone marrow
Can cause aplastic crisis
Roseola
Herpes virus type 6
Common in young children
Abrupt, high fever followed by rash, sometimes covulsions
No vaccine, treatment to reduce fever
Warts Agent
Papillomavirus
Papovirus family
SMall, nonenveloped, dsDNA
Can survive on fomites
Warts Pathogenesis
Infects deeper cells of epidermis
Reproduces inside cell nucleus
Infected cell grows abnormally
2-18 month incubation
Wart Treatment
Killing abnormal cells
Freezing, cauterizing, surgical removal
Superficial Cutaneous Mycoses Agent
Epidermophyton
Microsporum
Trichophyton
Known collectively as dermatophytes
Superficial Cutaneous Mycoses Symptoms
Itching
Odor
Rash
Some show no symptoms
Superficial Cutaneous Mycoses Pathogenesis
Skin is normally resistant
Excess moisture allows invasion of keratinized tissue
Keratinase - metabolizes keratin
Difuse to dermal layer and evoke immune response
Superficial Cutaneous Mycoses Prev/Treat
Attention to cleanliness
Keeping dry
OTC medications