Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
33 Cards in this Set
- Front
- Back
|
acronym for the "other" anticonvulsant drugs?
|
Can The Force of Gravity Pull The Levatating Zona Lower
|
|
|
What is CTFGPTLZL
|
-Clonazepam
-Topiramate -Felbamate -Gabapentin -Pregabine -Tiagabine -Levetiracetam -Zonisamide -Lamotrigine |
|
|
Seizures treated by Clonazepam
|
Absence seizures
Myoclonic seizures |
|
|
2 adverse effects of Clonazepam
|
-Tolerance w/ repeat doses
-Sedation |
|
|
Mechanism of Clonazepam
|
Increases inhibition by enhancing GABA activity
|
|
|
Seizures/condition treated by Topiramate:
|
-Adjunct for partials
-Migraine prevention |
|
|
Mechanism of Topiramate:
|
Blocks Kainate/AMPA receptors to decrease excitation
|
|
|
Seizures treated by Felbamate:
|
REFRACTORY partial seizures only
|
|
|
2 side effects of Felbamate
|
-aplastic anemia
-hepatic failure |
|
|
Mechanism of Felbamate:
|
Blocks Glycine receptor of NMDA receptor - decreases excitation
|
|
|
Seizures/conditions treated by Gabapentin:
|
-Partials alone
-Partials with Tonic/Clonics -Neuropathic pain |
|
|
Mechanism of Gabapentin:
|
Not sure, but not at GABA
|
|
|
Why no adverse effects of Gabapentin:
|
-No protein binding
-No metabolism |
|
|
Seizures/condition treated by Pregabalin:
|
-Adjunct for Partials
-Neuropathic pain in diab, postherpetic, fibromyalgia |
|
|
Pregabalin mechanism:
|
May act at voltage gated Ca channels
|
|
|
Tiagabine mechanism:
|
Blocks GABA reuptake - increased inhibition
|
|
|
Seizures treated by Levetiracetam:
|
-Adjunct for Partials
-Adjunct for Myoclonics |
|
|
Seizures treated by Zonisamide:
|
-Adjunct for Partials
|
|
|
2 Side effects of Zonisamide:
|
-Ataxia
-Speech impairment |
|
|
Mechanism of Zonisamide:
|
-Inhibits T-type and Na channels - decreases excitation
|
|
|
Seizures/condition treated by Lamotrigine:
|
-Partials monotherapy
-Absence monotherapy -Bipolar disorder |
|
|
Adverse effect of Lamotrigine
|
Rash/Steven johnson syndrome
|
|
|
Mechanism of Lamotrigine:
|
Much like phenytoin; inhibits Na channel to decrease repeated AP generation
|
|
|
Drug used for Status epilepticus
-stop the seizure -control the seizure |
Stop: Diazepam/Lorazepam IV
Control: Fosphenytoin IV |
|
|
Tiagabine mechanism:
|
Blocks GABA reuptake - increased inhibition
|
|
|
Seizures treated by Levetiracetam:
|
-Adjunct for Partials
-Adjunct for Myoclonics |
|
|
Seizures treated by Zonisamide:
|
-Adjunct for Partials
|
|
|
2 Side effects of Zonisamide:
|
-Ataxia
-Speech impairment |
|
|
Mechanism of Zonisamide:
|
-Inhibits T-type and Na channels - decreases excitation
|
|
|
Seizures/condition treated by Lamotrigine:
|
-Partials monotherapy
-Absence monotherapy -Bipolar disorder |
|
|
Adverse effect of Lamotrigine
|
Rash/Steven johnson syndrome
|
|
|
Mechanism of Lamotrigine:
|
Much like phenytoin; inhibits Na channel to decrease repeated AP generation
|
|
|
Drug used for Status epilepticus
-stop the seizure -control the seizure |
Stop: Diazepam/Lorazepam IV
Control: Fosphenytoin IV |
