4.7 Oncology

Front 1

Which Cancers is Hypercalcaemia most

common?

Back 1

1. Bone : multiple myeloma
2. Bony metastasis
a. Breast
b. Lung
c. Prostate
d. Renal
3. Parathyroid-like -secreting tumours
a. lung {SCC}
4. Osteoclastic factor-secreting tumours
a. lymphomas

Front 2

Which cancers is Tumour lysis syndrome most common?

Back 2

1. High cell turnover
a. Leukaemia
b. lymphoma
2. High tumour burden

"recent chemotherapy"

Front 3

What Metabolic / Biochemical abnormalities

occur with Tumour lysis Syndrome ?

Back 3

1. Acute Renal failure
2. Hyperkalaemia
3. Hyperuricaemia
4. Hyperphosphataemia
5. HYPOCALCAEMIA

Front 4

Which cancers are at risk of SVC Syndrome?

Back 4

1. Lung Ca.
2. Lymphoma

Front 5

DDx for Breathlessness in Oncology patient?

Back 5

1. PE
2. SVC syndrome
3. Malignant pericardial effusion
4. Malignant pleural effusion
5. Airway obstruction from tumour.

Front 6

DDx for Altered mental state in

Oncology

patient ?

Back 6

1. Hypercalcaemia
2. Hyponatraemia [ SIADH]
3. CNS malignancy
4. Infection
5. SVC Syndrome

Front 7

Mx Hypercalcaemia ?

Back 7

1. IV fluids NaCl 2-4 L
2. Bisphosphonates - Pamidronate

3. Steroids [ * NOT FOR SOLID TUMOURS]
4. Calcitonin
5. Haemodialysis { with ARF}

Front 8

Mx Tumour Lysis Syndrome ?

Back 8

1. IV fluids
2. Loop diuretics

3. Allopurinol**
4. Haemodialysis

Front 9

Mx SVC Syndrome ?

Back 9

1. IV steroids - dexamethasone
2. Frusemide
3. Intubation
4. Emergent radiation therapy **

Front 10

Mnemonic for Hypercalcaemia:

"Bony Mets

Produce Very Big Calcium"

Back 10

1. B bone disease [ metastasis]
2. M myeloma / milk alkali syndrome
3. P parathyroid [ primary OR PTHrp]
4. V vitamin D excess
5. B Benign familial hypercalcaemia
6. C chronic renal failure

[ tertiary hyperparathyroidism]