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18 Cards in this Set

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18 yo G2P1 at 35 weeks gestation with + hx of Graves disease
under treatment with oral PTU
has been feeling tachycardic and like her heart is pounding
has nervousness, sweating etc.
BP is 150/110
Hr 140
low grade fever
Thyroid is tender and enlarged. What is the dx?
thyroid storm
What is the treatment for thyroid storm?
B blockers, steroids and PTU
most common cause of hyperthyroidism in the US
Graves
signs of Graves
exophthalmos
non tender goiter
uniformly enlarged thyroid
What is the hallmark of thyroid storm vs simple hyperthyroidism
you get unstable vitals
So again what are we gonna do for this lady?
propanolol for her severe tachycardia and htn
steroids and additional PTU
What about in a non-pregannt patient?
it's exactly the same except that you can also use potassium iodide in these patients.
How would you interpret a high WBC in these patients?
they may also have BONE MARROW APLASIA

no bueno
2 most commonly used drugs for hyperthyroidism
PTU and methimazole
What is the difference between the two?
PTU has some peripheral conversion inhbition as well so it has a dual effect
do we use PTU or MMZ more often in pregnant patients?
PTU
Why use PTU if it has peripheral effects as well?
because methimazole can cause aplasia cutis
What are some sequellae of thyroidectomy?
hypothyroidism
hypoparathyroidism
vocal cord paralysis
Where should these ptients be managed with thyroid storm>
the ICU
What can you do if the fetus appears to devleop hypOthyroidism?
you can give intra-amniotic injections of T4/T3