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16 Cards in this Set
- Front
- Back
resting membrane potential (RMP) description
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the difference between the charge inside and outside the membrane
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in RMP the inside of sarcolemma is more ____ than outside
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negative
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in RMP there are more ____ ions outside the cell
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positive
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3 steps for action potential generation
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depolarization - propagation - repolarization
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action potential generation initial 3 steps
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Ach released by motor neuron - binds to receptors on motor end plate - sodium ion channels open and allow sodium to enter sarcolemma
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apg step 1 depolarization 4 details
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sodium gates open - influx of sodium - inside of sarcolemma becomes less negative - sudden positive change in membrane potential is depolarization
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apg step 2 propagation 4 details
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the depolarization wave spreads to adjacent areas - depolarization travel down sarcolemma - reaches t-tubules + terminal cisternae - causes release of calcium into the sarcoplasm
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apg step 3 repolarization 5 details
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occurs immediately following depolarization - sodium gates close - potassium gates open (diffuses out) - sodium-potassium pump moves sodium out + potassium in to restore RMP - RMP becomes negative once again
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absolute refractory period occurs during
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repolarization
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during absolute refractory period muscle fiber does not respond to
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stimulus
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depolarization summary
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membrane potential becomes more positive
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propagation summary
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depolarization travels down sarcolemma + t-tubules deep into the muscle fiber
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repolarization summary
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RMP is restored back to its negative state
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acetylcholinesterase (AchE) description
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enzyme that breaks down ACh
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what prevents continuous muscle contraction
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acetylcholinesterase
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acetylcholinesterase (AchE) prevents further nerve stimulation needed to continue
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contraction
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