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16 Cards in this Set

  • Front
  • Back
resting membrane potential (RMP) description
the difference between the charge inside and outside the membrane
in RMP the inside of sarcolemma is more ____ than outside
negative
in RMP there are more ____ ions outside the cell
positive
3 steps for action potential generation
depolarization - propagation - repolarization
action potential generation initial 3 steps
Ach released by motor neuron - binds to receptors on motor end plate - sodium ion channels open and allow sodium to enter sarcolemma
apg step 1 depolarization 4 details
sodium gates open - influx of sodium - inside of sarcolemma becomes less negative - sudden positive change in membrane potential is depolarization
apg step 2 propagation 4 details
the depolarization wave spreads to adjacent areas - depolarization travel down sarcolemma - reaches t-tubules + terminal cisternae - causes release of calcium into the sarcoplasm
apg step 3 repolarization 5 details
occurs immediately following depolarization - sodium gates close - potassium gates open (diffuses out) - sodium-potassium pump moves sodium out + potassium in to restore RMP - RMP becomes negative once again
absolute refractory period occurs during
repolarization
during absolute refractory period muscle fiber does not respond to
stimulus
depolarization summary
membrane potential becomes more positive
propagation summary
depolarization travels down sarcolemma + t-tubules deep into the muscle fiber
repolarization summary
RMP is restored back to its negative state
acetylcholinesterase (AchE) description
enzyme that breaks down ACh
what prevents continuous muscle contraction
acetylcholinesterase
acetylcholinesterase (AchE) prevents further nerve stimulation needed to continue
contraction