4.4 H) Neurological Seizures

Front 1

7 Main groups for Secondary causes of Seizures

Back 1

1. Metabolic
2. Drugs/Toxins
3. CNS Infection
4. CNS Lesion / Event
5. Febrile Seizures {Paediatric}
6. Trauma
7. Eclampsia

Front 2

Metabolic Causes of Seizures {3}

Back 2

1. Hypoglycaemia
2. Hyponatraemia
3. Hypocalcaemia

Front 3

Drugs / Toxins causing secondary seizures

Back 3

1. Anticholinergics
2. Cholinergics
3. Sympathomimetics
4. Antidepressants
5. Withdrawal Syndromes
6. Mushrooms
7. Toxic alcohols
8. Isoniazid

Front 4

CNS Lesions / Events causing secondary seizures.

Back 4

1. Haemorrhage
2. Tumour
3. Stroke
4. Vasculitis
5. Hydrocephalus
6. Neurocysticercosis

Front 5

Which rash is not seen in phenytoin dermatological manifestations?
1. Morbilliform {measles-like}
2. Stevens-Johnson Syndrome
3. Toxic epidermal necrolysis {TEN}
4. Bullous dermatitis
5. Scarlatiniform rashes

Back 5

All can be seen!

Front 6

Which is incorrect regarding phenytoin?
1. It can only be given with normal saline
2. Acute alcoholic intake may increase phenytoin serum levels.
3. Chronic alcohol abuse can decrease serum phenytoin levels.
4. It is not indicated for toxicological seizures.
5. It's maximum infusion rate is 100mg/min

Back 6

5. 50 mg/min
{ 25mg/min in CVS disease and the elderly}

Front 7

Drugs which INCREASE phenytoin levels?

Back 7

1. Acute alcohol intake
2. Warfarin
3. Diazepam
4. Amiodarone
5. H2 Antagonists
6. {Other- sulfonamides; isoniazid}

Front 8

Drugs which DECREASE phenytoin levels?

Back 8

1. Chronic alcohol abuse
2. Carbamazepine

Front 9

Drugs which can have a variable effect to increase or decrease phenytoin serum levels.

Back 9

1. Valproate
2. Phenobarbitol

Front 10

Drugs whose efficacy is impaired by phenytoin?

Back 10

1. Warfarin
2. Corticosteroids
3. Frusemide
4. OCP
5. Rifampicin
6. Theophylline