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12 Cards in this Set

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Where does the paramesonephric duct arise from? What do the ducts become?
ARISE from intermediate mesoderm.

DELEVOP INTO upper 2/3 of vagina, cervix, and uterus, and fallopian tubes
What hormone drives mesonephric duct development?
Testosterone
What hormone drives paramesonephric duct development?
The ABSENCE of MIS/AMH (produced by sertoli cells)
At 5-6 weeks, is embryo differentiated?
NO.

Both ducts (para and meso) are present.
How do the sinovaginal bulbs form?
When the uterovaginal primordium (from the fused ends of the paramesonephric ducts) joins the coelemic epithelium.

If sinovaginal bulbs do not form, this results in vaginal agenesis.
Where do fallopian tubes arise from?
They arise from paramesonephrics...the unfused portion of the upper ducts.
What do the sinovaginal bulbs form?
When they fuse, they form the vaginal plate.

Central cells undergo apoptosis to form the vaginal lumen.
What are the TWO GENERAL CATEGORIES of mullerian abnormalities?
Vertical and horizontal abnormalities
What is a key characteristic of VERTICAL MULLERIAN ABNORMALITIES.
Problems with connection of vertical structures
i.e.

1) transverse vaginal septum
2) Cervical agenesis/dysgenesis
3) Mullerian AGENESIS!
4) Imperforate hymen.

ALL THINGS THAT WOULD PREVENT YOU FROM GOING UP.
What is a key characteristic in HORIZONTAL MULLERIAN ABNORMALITIES.
Both side DO NOT come together evenly. There may be a longitudinal uterine septum. There may be
Uterine didelphis has how many vaginas?
TWO
What is the difference between a bicornuate uterus and a septum uterus?
Bicornuate is a heart-shaped uterus. The ducts have fused in the CAUDAL portion. However, the CRANIAL PART REMAINS UNFUSED. The uterus looks like a heart.

The SEPTUM uterus has fused completely, although tissue separates both sides. Can cause TOTAL COMPARTMENTALIZATION.