370 Ped10A

Front 1

H&A dysfunction – CBC

Back 1

usually lower 1. neutrophil 2. leukocytes 3. tcell 4. hemoglobin 5. platelet

Front 2

H&A dysfunction – history and phys exam

Back 2

1. decr energy = decr Hg

Front 3

H&A dysfunction – infections freq

Back 3

1. rt decr neutrophils

Front 4

H&A dysfunction – bleeding

Back 4

pale

Front 5

RBC disorders – anemia

Back 5

1. most common hema disorder of childhood 2. decr RBC and/or decr [Hgb] below normal 3 decr o2 carry capacity

Front 6

Anemia – patho

Back 6

1. rbc and/or hgb depletion

Front 7

Anemia – morph

Back 7

1. changes in rbc size, shape, or color

Front 8

Anemia – management

Back 8

1. treat underlying cause/ transfusion or nutrition 2. supportive care: IV for intravacular volume, o2, rest

Front 9

Anemia – nurse care

Back 9

1. prep child for lots of test 2. decr o2 demand 3. give reward 4. prev complications 5. support family

Front 10

Anemia – iron deficiency

Back 10

1. decr dietary Fe+ 2. iron cereals/formula for children 3. premie special 4. ado poor habits/rapid grow

Front 11

Anemia – iron def path

Back 11

multiple factors

Front 12

Anemia – aplastic

Back 12

1. aka bone failure 2. all elements depressed: hgb, wbc, plate 3. anemia 4. leukopenia 5. thrombocytopenia

Front 13

Anemia – hypoplastic

Back 13

1. depression of RBC 2. normal wbc and platelet

Front 14

Anemia – aplastic etiology

Back 14

1. primary/congenital 2. secondary/acquired

Front 15

Anemia – aplastic dx

Back 15

1. bone marrow aspirate/biopsy

Front 16

Anemia – aplastic therapeutic ment

Back 16

1. immunosuppresives 2. bone marrow transplant

Front 17

neoplastic disorders

Back 17

1. leading COD from disease past infancy 2. half of child cancer = blood/blood forming organs

Front 18

leukemia

Back 18

1. most common child cancer 2. usu white 3. less than 15 4. more males over 1yo 5. peak 2-5yo

Front 19

Leukemia – classification

Back 19

1. broad group of malignant disease of marrow and lymph 2. multiple origins 3. hard to classify

Front 20

Leukemia – morphology

Back 20

1. acute lymphoid leukemia ALL 2. acute nonlymphoid/myelogenous leukemia ANLL/AML 3. stem/blast cell leukemia (ALL)

Front 21

ALL

Back 21

1. lymphatic 2. lymphocytic 3. lymphoblastic 5. lymphoblastoid 6. better if child

Front 22

AML/ANLL

Back 22

1. granulocytic 2. myelocytic 3. monocytic 4. myelogenous 5. monoblastic 6. nonmyeloblastic

Front 23

Leukemia – chromosome studies

Back 23

1. down/trisomy 21 = 20x risk of ALL 2. more than 50 chromosomes = best prognosis 3. translocations of chromo on leukemic cells can affect prognosis

Front 24

Leukemia – patho

Back 24

1. unrestricted prolif of immature WBC in blood form tissues 2. usu liver/spleen 3. acute form may have low leuk count due to high blast 4. cell death – infiltration/competition for metabolic elements

Front 25

Leukemia – consequences

Back 25

1. anemia from decr rbc 2. infect from netropenia 3. bleed from decr plate 4. spleen/liver/lymph show infiltration/enlarge/fibrosis

Front 26

Leukemia – dx

Back 26

1. based on history, physical manifest 2. periph blood smear = imm leuk/many lo blood count 3. lumbar punc to eval CNS 4. marrow asp/biopsy

Front 27

Leukemia – therapeutic ment

Back 27

1. chemo risks and secondary cancer possible 2. cranial irradiation usu not 3-7yo if possible

Front 28

Leukemia – 4 phases of therapy

Back 28

1. induction 4-6w 2. CNS prophylactic therapy: intrathecal chemo 3. intensification/consolidation therapy: prevent residual/kill resistant 4. maintenance therapy: up to 3y

Front 29

Leukemia – prognosis

Back 29

1. if relapse after hsct = dismal 2. factors: initial WBC, age, type of cells, gender, karyotype analysis

Front 30

lymphoma

Back 30

1. enlarge lymph cancer 2. hodgkins 3. NHL

Front 31

hodgkins age

Back 31

usu 15-19yo

Front 32

NHL age

Back 32

less than 14

Front 33

hodgkins def

Back 33

1. neoplastic 2. origin lymph 3. metastisize: spleen, liver, marrow, lungs

Front 34

hodgkins dx

Back 34

1. lymph node biopsy for dx/staging 2. reed-stenberg cell = characteristic

Front 35

hodgkins therapeutic ment

Back 35

1. rad 2. chem 3. chemo/rad

Front 36

lymphoma nursing care

Back 36

1. educate 2. care 3. repeat info 4. check child fatigue

Front 37

NHL ratio

Back 37

1. 60% of ped lymphoma

Front 38

NHL dx

Back 38

1. diffuse not nodular 2. cells undifferentiated 3. disseminate early, often, rapid 4. medistinal involved .invasion of meninges