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9 Cards in this Set
- Front
- Back
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how does the structure of colesterol compare to that of ergosterol?
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ergosterol has 2 double bonds and one methyl more than cholesterol, p 257
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which enzyme in ergosterol biosynthesis is sensitive to inhibiton? what happens when inhibit?
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14 demethylase, remove 14 alpha methyl group of ergosterol precursor
so intermediate accumulate, and no ergosterol, intermediate that are methylated sterols can buildup and ruin cell membrane |
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does 14 demethylase inhibitors affect mammals?
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no, only affect fungi
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give example of 14 demethylase inhibitor
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imidazoles, triazles, pyrimidines, piperazines
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what is another inhibitor of ergosterol binsynthesis that does not inhibit 14 demethylase?
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morpholines
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what is backbone structure of triazoles, imidazoles, pyrimidines, piperazines, and morpholines?
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p. 258
triazoles and imidazoles- n heterocycle with 2 apolar substituents |
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give example of triazoles, imidazoles, pyrimidines, piperazines, and morpholines
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triazoles and imidazoles: triamedifion, propiconazole, imazil, triadimenol
pyrimidines: fenarimol, nuarimol piperazine: triforine morpholines: tridemorph |
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what are property and uses of triazoles and imidazoles, pyrimidines, piperazines, and morpholines
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triazole and imidazole: systemic with high potency, broad spectrum, protective and curative properties, work on mildew and rusts on vegies cereals deciduous fruits, grapes, ornamentals
pyrimidines: systemic, protective erdicating powdery mildew on cereals, scab, rusts of apples, other deciduous fruit, works on turf diseases piperazine: systemic(apoplastic, somwhat symplastic) of powdery mildow very potent morpjoline: inhibit sterol biosynthesis at different site than majority of ergosterol biosynthesis sites, systemics with curative and preventative qualities for powdery mildew tridemorph (affect fungal cell wall) for mildew of barley oats winter wheat dodemorph for powdery mildew (roses) |
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how does acibenzolar s methyl benzothiadiazole alter endogenous salicycli acid and its effect in host-pathogen interactions?
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endogenous salicyclic acid plays crucial role in induction process whch gives resistance to pathogen infection, compound alters salicyclic acid and induces plant reponse to fill fungus
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