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19 Cards in this Set
- Front
- Back
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chronic thromboembolic pulm htn is complication from |
PE type of pulm arterial htn |
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interventricular septum flattened consistent with |
RV overload |
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pulm vascular resistance is what compared to systemic |
1/10th |
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normal pressure valvues |
RA 2 RV 25/0 LA 5 LV 120/0 |
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pulmonary arterial htn |
elevated mean pulp artery pressure > 25 when normal is 8-20 |
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if you suspect pulm htn what to do? |
hemodynamic profile clinical context
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PAH is |
subgroup of PH dz state of small pulm aa vascular narrowing and increased resistance. causes RV failure and death |
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chronic thrombembolic pulm htn CTEPH |
after 3 months of anticoag
mPAP >25 with PCWP <15
V/Q mismatch |
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PAH causes |
genetic- ALK, BMPR2 schistosomiasis chronic hemolytic anemia pulm veno-occlusive PVOD |
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PAH really |
imbalance of vasconstriction and vasodilators
endothelin pathway: vasonconstriction NO: vasodilator prostacyclin pathwya: vasodilator |
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how does PAH look in histo |
intimal fibrosis medial thickness increase pulm arteriolar occlusion plexiform lesions |
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CTEPH |
small dz, blocks in airways |
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the central role in severe p HTN |
dysfunctional endothelial cells |
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most PH is from |
left heart dz |
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PAH pts die from |
RV failure |
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who gets PAH |
females HIV anorexigens congenital heart dz portal htn thyroid disorder cocaine |
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CTEPH risks |
splenectoy pacemaker device infxn thyroid hormone replacement |
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how to screen PAH
how to dx
CTEPH |
echo biomarkers
right heart catherterization to do PCWP and RAP RVP PAP CO
then try a vasodilator and see if fixes -- V/Q scan, CT angiography |
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tests that are a waste |
EKG CXR |
