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18 Cards in this Set
- Front
- Back
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Which viruses cause intraCYTOPLASMIC inclusions?
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just rabies
Negri bodies |
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What is the major oncogene in Burkitt's lymphoma?
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c-myc on chromosome 8
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How does HPV lead to cancer?
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HPV 16 and 18 inhibit E2, which suppresses E6 and E7, E6 suppresses p53 and E7 suppresses Rb
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HHV8 associated with what?
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Cyclin protein inhibits Rb
Body cavity B cell lymphoma |
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What is Bcl-2?
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anti-apoptotic
associated with HHV8, EBV |
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HBV vs HCV outcome?
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HBV can go straight from chronic to HCC
HCV goes from chronic to cirrrhosis to HCC |
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Main drug resistance method for chloroquine?
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efflux pump
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Which anti-malarial can cause fatal hemolysis?
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Primaquine in G6PD deficiency
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Dx of WNV?
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ELISA detection of IgM
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What's so special about hantavirus dx?
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confirmatory testing must be done by CDC or AZ health lab
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Vector of RMSF in az?
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Dog tick
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Tx of RMSF?
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tetracyclines, DO NOT WAIT FOR LAB CONFIRMATION
treat clinically |
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Dx of lyme disease?
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2 tier:
EIA or IFA Western |
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Diagnostic criteria of Dengue?
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Fever
Hemorrhagic manifestations Thrombocytopenia Increased hematocrit Low albumin Pleural effusions |
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Dx of Dengue?
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IgM ELISA
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Most common cause of bacterial infxn 2ndary to viral?
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Staph aureus
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Rhinorrhea with SARS?
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no
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Tx for east african trypanosomiasis
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Suramin (blood)
Melasoprol |
