2155 Ob/mcc Exam 2 Part 10

Front 1

A chronic lung condition occuring in premature infants weighing less then 700g at birth is ? dysplasia/? lung disease. Infants generally require O2, CPAP. A MAJOR SIGN is increased need for ? or an inability to be ?d from the ventilator. Try and get baby off ? ASAP

Back 1

Bronchopulmonary Dysplasia/Chronic lung Disease,
ventilation,
weened,
ventilation

Front 2

Prevention of BPD/Bronchopulmonary Dysplasia include giving mom ?s to enhance fetal lung maturity. Upon birth give minimal exposure to ? and ?, avoid ? overload. The infant may go home on a ? and may have gradual improvement with ? and may have many ? infections.

Back 2

steroids,
O2, ventilation,
fluid, ventilator,
age, respiratory

Front 3

Periventricular-Intraventricular Hemorrhage also called germinal matrix hemorrhage/intraventricular hemorrhage occurs most often in infants less than ? weeks or <?g The first ?hrs are the most common times of hemorrhage. It is less frequent/severe when perinatal ?s are administered.

Back 3

<32wks,
<1000g,
72hrs,
steroids

Front 4

PIVH results from rupture of the fragile blood vessels in the germinal matrix, located around the ventricles of the ? which leaks into the cranial cavity.

Back 4

brain

Front 5

Risk factors for PIVH in addition to prematurity: if the baby needed ?, infusion of ? solution, ?/?, mechanical ?, pneumo-? Any of these increase risk for PIVH.

Back 5

resuscitation, hyperosmolar, apnea/bradycardia,
ventilation, pneumothorax

Front 6

The PIVH is graded ?-? accoding to the amount of bleeding. A very small amt of bleeding at the germinal matrix is grade ?, If the hemorrhage extends into the lateral ventricles it is a grade ?, if it causes distention of the ventricles it is grade ?, if it causes ventricular dilation and extends into surrounding brain tissue it is grade ?

Back 6

1-4,
1,
2,
3,
4

Front 7

Grade ? and ? PIVH may have ? abnormalities and ? delays.

Back 7

3 and 4,
neurologic,
developmental

Front 8

A serious imflammtory condition of the intestinal tract in preterm infants is called ? The terminal ? and proximal ? are the areas most affected. It is usually seen in infants that are <?g.

Back 8

Necrotizing enterocolotis,
ileum, colon,
<1500g

Front 9

S/S of necrotizing enterocolitis include: ? intolerance, bile colored ?, abdominal ?, ? or ? shock, ? in stool, ? instability.

Back 9

feeding, vomitus,
distension, septic or hypovolemic,
blood, temperature

Front 10

NEC is less likely to occur in ? fed infants

Back 10

breast

Front 11

Retinopathy of prematurity(ROP) occurs more frequently in infanst <?g. It is caused by damage to immature blood vessels in the ? There is ? and there is permanent ?. High levels of ?, ?, prolonged ? ventilation, ? and ? can cause ruptures.

Back 11

<1000g,
retina, hemorrhage, damage,
O2, Acidosis,
mechanical, sepsis, shock

Front 12

ROP requires close monitoring of ? oximetry, and close follow up with ? if baby has been in or is in NICU.

Back 12

pulse,
opthamology

Front 13

Would a premature infant have the same developmental milestone timeframe as a full term infant?

Back 13

No, they must be adjusted for age.

Front 14

Chromosomes are composed of ? that are composed of ?

Back 14

genes, Deoxyribonucleic acid(DNA)

Front 15

Genes are organized into ? paired chromsosomes, ? from each parent. ? chromosome pairs are autosomes, the ? pair is the sex chromosome. Female = ?,? Male= ?,?

Back 15

46,
23,
22, 23rd,
46XX,
46XY

Front 16

Genotype vs. Phenotype: Your genetic constitution,"", what you are made up of inside is your ? and the observable characteristics, what you look like on the outside is your ?

Back 16

Genotype,
Phenotype

Front 17

The building block of genes and chromsomes is ?

Back 17

DNA

Front 18

The human genome project is an international effort begun in 1990 to identify all ? contained in the ? chromosomes. This may help us to identify people who have the gene specific to a ? or it they are a carrier of a ? Identifying genes may show a ? that a person has and a need to make a ? change. This project could also lead to gene ?, and modifying the defective gene.

Back 18

genes,
46,
disorder, disease,
predisposition, lifestyle,
therapy

Front 19

Ethical concerns with the identifying problem causing genes: What if testing identifies a fetal disease with no tx? should testing be required prior to conception?
Substituting one human gene for another e.g. designer babies? Who should own and control genetic info? e.g. patient, physician, Insurance Co.
How should issues of racil/ethic identification be handled? should parents have the right to have their minor childeren tested for adult-onset diseases?

Back 19

open for discussion

Front 20

An autosomal ? trait is produced by a dominant gene on a non-? chromosome. ? mutated copy of the gene in each cell is sufficient for a person to be affected by an autosomal dominant disorder. Each affected person must have ? affected parent. Autosomal dominant disorders tend to occur in ? generation of an affected family.

Back 20

dominant, non-sex,
One, One,
every

Front 21

With autosomal dominant traits a ? state does NOT exist. Affected individuals must have an affected ? One affected parent and there is a ?% chance of having an affected child. Two affected parents and there is a ?% chance of having an affected child. Normal children of an affected parent have a ?% chance of having affected children.

Back 21

carrier,
parent,
50%, 75%,
0%

Front 22

One parent with an autosomal dominant trait and one parent without = a ?% chance of the expression.
Two parents with an autosomal dominant trait there is a ?% chance of the expression. Draw a punt square to figure it out using B=parent with dominant gene, b=parent without dominant geen pg 5 of genetic power point.

Back 22

50%,
75%