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10 Cards in this Set
- Front
- Back
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What kind of pain are nonnarcotic analgesics used for?
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Headaches, dysmenorrhea, inflammation, minor abrasions, muscular aches and pain, mild to moderate arthritis
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What effects do NSAIDS have?
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Analgesic effect, antipyretic and anti-inflammatory effect
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What are OTC versions of NSAIDs and salicylates?
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Aspirin (ASA), ibuprofens (Motrin IB, Nuprin, Advil, Medipren), naproxen (Aleve)
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What are examples of aspirin with added ingredients?
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Bufferin, Ecotrin (enteric coated), Anacin (contains caffeine), Alka-Seltzer
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In which age group should aspirin not be used and why?
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In children younger than 12yrs bc of Reye syndrome (neurologic problems associated w viral inf and treated w salicylates). Acetaminophen (Tylenol) is used instead.
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Aspirin and other NSAIDS releive pain by inhibiting the cyclooxygenase used for the biosynthesis of prostaglandins. What is the function of the two enzyme forms?
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COX-1 protects the stomach lining and promotes blood clotting. COX-2 triggers pain and inflammation at the injured site.
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What happens when COX-1 or COX-2 is blocked?
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When COX-1 is blocked, there is stomach bleeding and ulcers. When COX-2 is blocked, pain and fever are reduced and inflammation is suppressed.
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What are examples of COX-2 inhibitors? Who would not benefit from taking aspirin?
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celecoxib (Celebrex), meloxicam (Mobic), nabumetone (Relafen)
People at risk for stroke ro heart attack |
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What are common side effects of aspirin and NSAIDs?
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Gastric irritation
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What indicates hypersensitivity or overdose of aspirin (salycylate)?
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Tinnitus, vertigo, bronchoaspasm, urticaria
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