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15 Cards in this Set

  • Front
  • Back
What does hemocholium do?
blocks CHT (choline transporter)
What does Vesamicol do?
blocks VAT (vesicular Acetylcholine transferase
What does botulinum do?
cleaves SNARE & SNAP proteins preventing acetylcholine vesicles to be released!
Which enzyme responsible for making acetylcholine?
ChAT (Choline acetyal transferase)
What is the enzyme that makes DOPA?
tyrosine hydrolase
Where is Norepinephrine (NE) made?
inside the vesicle
What does Reserpine do?
it blocks VMAT on the membrane of the vesicle
What does Metyrosine do?
It blocks tyrosine hydroxylase
What does cocaine, tricyclic antidepressants have in common? (in term of of acting this protein on the membrane fo a presynaptic vesicle)
it blocks NET
What do bretylium and guanethidine do?
they block the releases of adrenergic vesicles
Both acetylcholine & adrenergic vesicles are stored with ATP. T/F
True
What do amphetamines & tyramine do to the release of adrenergic vesicles?
They increase the release
Wthich compound is measured in urine to estimate the amount of catecholamine metabolism?
3-methoxy-4-hydroxy-mandelic acid - vanillylmandelic acid, for short (VMA)
Receptors regulating the synthesis and/or the release of mediators other than its own ligand are called what?
heteroreceptors
What are trophotropic and ergotropic?
mechanisms and the functional status of the nervous system that favor the organism's capacity to conserve and expend energy - referring to parasympathetic & sympathetic, respectively