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23 Cards in this Set
- Front
- Back
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Person (any age/sex) with history of sepsis or multiple gunshot wounds (or multiple blunt trauma, or uremia, etc) develops SUDDEN fulminate respiratory failure requiring mechanical ventilation.
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Diffuse Alveolar Damage, Acute Respiratory Distress Syndrome
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35 yo male with Hx of upper respiratory tract infection a few months ago, presents with cough (x a few weeks) which does not resolve with antibiotics, patchy infiltrates on CXR.
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Bronchiolitis Obliterans-Organizing Pneumonia (BOOP)
Loose plugs of fibroblastic tissue fill alveolar spaces and bronchi/bronchioles |
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45 yo black female presents with worsening SOB and cough for several months. Bilateral infiltrates and hilar adenopathy on CXR.
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Sarcoidosis
(Non-caseating granulomas) |
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40-70 yo (male), insidious onset of progressive dyspnea. CXR: bilateral patchy infiltrates, more pronounced in lower lobes and peripheral lung zones. (Temporal heterogeneity.)
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Idiopathic interstitial Fibrosis
(Usual Interstitial Pneumonia) Ultimately fatal. |
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35 yo male heavy smoker, presents with worsening dyspnea for several months. CXR shows bilateral ground glass infiltrates in lower lobes.
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Desquamative Interstitial Pneumonia
** associated with smoking !! ** Excellent outcome. |
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40 yo female with history of Sjogren's Syndrome, presents worsening SOB/cough for several months.
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Lymphocytic Interstitial Pneumonia
Mainly in children w/ AIDS or adult with AIDS/Sjogrens Lymphoma may complicate |
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25 yo male heavy smoker, presents with pneumothorax, radiographs shows nodules and cysts
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Langerhans Cell Histiocytosis
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Person with constant occupational/recreational exposure to allergens. Acute fever, dyspnea, cough, leukocytosis.
* bronchocentric chronic inflammation/fibrosis * organizing pneumonia * poorly formed granulomas |
Hypersensitivity Pneumonitis
(extrinsic allergic alveolitis) Chronic disease may be independent of allergen exposure. |
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Transient migratory pulmonary lesions, peripheral blood eosinophils. Minimal symptoms
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Simple pulmonary eosiniphilia -- Loeffler's Syndrome
may be associated with ascarid larval migration |
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High fever, cough, wheezing, dyspnea.
Migratory infiltrates, high peripheral blood eosinophils. |
Tropical pulmonary eosinophilia
usu. secondary to migratory parasites (microfilaria) |
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Acute fulminate like DAD
or chronic dz with insidious onset |
Eosinophilic pneumonia
may be idiopathic or due to underlying infections (fungal, parasitic), drug reactions, inhalant exposure |
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Bleomycin - pulmonary side effects
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Interstitial inflammation and fibrosis
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Methotrexate - pulmonary side effects
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Interstitial inflammation and fibrosis, with mild granulomatous response
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Amiodarone - pulmonary side effects
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Pulmonary fibrosis, foamy macrophages
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Radiation therapy (thoracic tumors) - pulmonary side effects
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Radiation pneumonitis --
Acute: like DAD Chronic: like UIP Fibrosis may contain bizarre vacuolated cells and atypical endothelial cells. |
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Rheumatoid arthritis - secondary lung disease
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pleuritis, BOOP, UIP-like fibrosis, rheumatoid nodules.
* rheumatoid nodules + pneumoconiosis == Caplari's Syndrome |
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SLE - secondary lung disease
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pleuritis, DAD, intra-alveolar hemorrhage, interstitial fibrosis.
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Scleroderma - secondary lung disease
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UIP-like interstitial fibrosis
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Sjogren's Syndrome - secondary lung disease
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pleuritis, LIP, lymphoma
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rapid-progressing glomerulonephritis and hemorrhagic interstitial pneumonia
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Goodpasture's Syndrome
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young males -- hemoptysis, no renal disease
(anemia in children) |
Idiopathis Pulmonary Hemosiderosis
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40~ yo male, with chronic sinusitis, hemoptysis, and renal disease. CXR shows bilateral cavitary infiltrates/nodules.
positive c-ANCA in blood * acute necrotizing granulomas of upper resp. tract * necrotizing/granulomatous vasculitis * renal disease (crescentric glomerulonephritis) |
Wegener's Granulomatosis
(If no renal dz: "limited WG") * Churg-Strauss (allergic angiitis and granulomatosis) - similar to WG, but with eosinophils - no renal disease - p-ANCA (not c) |
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non-specific distress of insidious onset.
Alveolar spaces diffusely filled with granular eosinophilic material (surfactant-like). Resembles pulmonary edema and consolidation of large areas of lung. May follow silicoproteinosis. |
Pulmonary Alveolar Proteinosis
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