2-Oral Path Vocabulary Ch3

Front 1

acantholysis

Back 1

dissolution of the intercellular bridges of the prickle cell layer of the epithelium.

Front 2

acquired immune response

Back 2

a response of the body to injury that has memory of past exposure to a foreign substance and responds more quickly to a foreign substance the second time.

Front 3

allergy

Back 3

hypersensitive state acquired through exposure to a particular allergen; reexposure to the same allergen elicits and exaggerated reaction.

Front 4

anaphylaxis

Back 4

severe hypersensitivity or allergic reaction; exaggerated immunologic reaction from release of vasoactive substances (histamine). occurs on reexposure after sensitizaton.

Front 5

antibody

Back 5

a protein molecule, also called an immunoglobulin, which is produced by plasma cells and reacts with a specific antigen.

Front 6

antigen

Back 6

any substance able to induce a specific immune response.

Front 7

autoantibody

Back 7

an antibody that reacts against an antigenic constituent of the persons own tissue.

Front 8

autoimmune disease

Back 8

a disease characterized by tissue injury caused by a humoral or cell-mediated immune response against constituents of the body's own tissue.

Front 9

B lymphocyte (B cell)

Back 9

a lymphocyte, that matures without passing through the thymus; the B cell can later develop into a plasma cell that produces antibodies.

Front 10

cell-mediated immunity

Back 10

immunity in which the predominant role is played by T lymphocytes.

Front 11

cytokine

Back 11

cell product produced by the cells involved in the immune response.

Front 12

humoral immunity

Back 12

immunity in which B lymphocytes and antibodies play the predominant role.

Front 13

hypersensitivity

Back 13

a state of altered reactivity in which the body reacts to a foreign agent with an exaggerated immune responce.

Front 14

immune complex

Back 14

a combination of antibody and antigen.

Front 15

immunodeficiency

Back 15

a deficiency of the immune response resulting from hypoactivity or decreased numbers of lymphoid cells.

Front 16

immunoglobulin

Back 16

a protein also called an antibody, synthesized by plasma cells in response to a specific antigen.

Front 17

LE cell

Back 17

a cell that is a chatacteristic of lupus erythematosus (LE) and other autoimmune diseases; it is a mature neutrophil that has phagocytized a spherical inclusion derived from another neutrophil.

Front 18

lymphoid tissue

Back 18

tissue composed of lymphocytes supported by a meshwork of connective tissue.

Front 19

macrophage

Back 19

large tissue-bound mononuclear phagocyte derived from monocytes in blood; become mobile when stimulated by inflammation & interact with lymphocytes in immune response.

Front 20

mucosistis

Back 20

mucosal inflammation

Front 21

matural killer cell (NK)

Back 21

a lymphocyte that is part of the body's initial innate immunity, which by unknown mechanisms is able to directly destroy cells recognized as foreign.

Front 22

nickolsky's sign

Back 22

in some bullous diseases such as pemphigus vulgaris and bullous pemphigus the superficial epithelium separates easily from the basal layer on exertion of firm, sliding manual pressure.

Front 23

rheumatoid factor

Back 23

a protein; immunoglobulin M (IgM), found in serum and detectable on laboratory tests; it is associated with rheumatoid arthritis and other autoimmune diseases.

Front 24

T lymphocyte (T cell)

Back 24

a lymphocyte that matures in the thymus before migrating to tissue; the T lymphocyte is responsible for cell-mediated immunity and may modulate the humoral immune response.

Front 25

thymus

Back 25

a lymphoid organ located high in the chest, which is large in an infant and gradually shrinks in size.

Front 26

xerophthalmia

Back 26

abnormal dryness of the eyes.

Front 27

xerostomia

Back 27

decreased salivary flow resulting in abnormal dryness of the mouth.