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22 Cards in this Set
- Front
- Back
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What are the 4 main inflammatory conditions of the breast?
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-Acute mastitis
-Periductal mastitis -Mammary duct ectasia -Fat necrosis |
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What 3 clinical symptoms are seen in Acute mastitis?
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-Erythema
-Pain -Fever |
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When is acute mastitis almost always seen?
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During lactation
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What 2 bacteria are associated with Acute mastitis, and which is more common?
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Staph aureus > Strep
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How is Acute mastitis treated?
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-Antibiotics
-Drainage of milk |
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What are 2 possible complications of Acute mastitis?
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-Localized abscess
-Diffuse infection |
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What are 90% of patients that get Periductal mastitis?
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Smokers!
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What are the 3 usual symptoms seen in periductal mastitis?
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-Erythema
-Pain -Subareolar mass |
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Why does the subareolar mass develop in periductal mastitis?
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Due to extention of squamous epithelium deep into the ducts.
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What are 2 complications of Periductal mastitis?
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-Nipple inversion
-Fistula formation |
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What is the treatment for Periductal mastitis?
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Antibiotics and Excision of the duct/fistula
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What causes a recurrent subareolar abscess to develop from periductal mastitis?
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When the squamous metaplasia produces much keratin which creates a keratin plug
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What type of inflammatory response develops in response to the keratin plug?
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Chronic granulomatous inflammation
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What is a Mammary Duct Ectasia?
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A Poorly defined periareolar mass with thick nipple secretions that can even be blue or green
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In what patients is mammary duct ectasia more likely to be seen?
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50-60 yr olds that have given birth to multiple infants.
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What type of morphologic changes are seen in mammary duct ectasia?
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-Duct dilation
-Lipid laden macrophages in duct -Periductal chronic inflammation and fibrosis |
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What is RARELY seen in the periductal chronic inflammation of mammary duct ectasia?
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Granulomas
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What does Fat necrosis in the breast often follow?
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Trauma or prior surgery
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How does Fat necrosis generally present clinically?
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As a painless palpable mass that mimics carcinoma because of skin thickening or retraction
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Why is fat necrosis often a cause of biopsy?
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Because when mammogram is done to investigate the palpable mass it often shows density or calcifications
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What is another thing that can cause calcification due to chronic inflammation?
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Reaction to silicone implants
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What type of inflammatory response will likely be seen in a silicone implant reaction?
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Granulomatous
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