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27 Cards in this Set
- Front
- Back
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Epithelial cell usually exhibit polarity--
what helps keep the apical and basolateral regions segregated? |
tight junctions
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True or False
epithelial tissue gain nourishment by diffusion of nutrients |
True
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Extra long microvilli are called
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stereocilia
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microvilli
stereocilia are made up of...? |
actin
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Primary Cilia
Motile Cilia Nodal Cilia are all made up of? |
microtubules
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primary cilia have an axoneme that has a ? microtubule arrangement
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9+0
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True or False
Primary cilia are NON-MOTILE |
true
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What type of transmembrane proteins do ZONULAE ADHERENS use for cell to cell adhesion?
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Cadherins
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True or False
Cadherins require the presence of CALCIUM for function |
true
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What are the linker / anchoring proteins that ZONULAE ADHERENS uses?
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catenins
α-actinin |
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Zonulae Adherens
Transmembrane protein:: cytoskeletal connection:: |
cadherins
F-actin (microfilaments) |
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Desmosomes
transmembrane proteins:: linker / anchor proteins:: cytoskeletal connection:: |
cadherin
desmoplakin , plakoglobulin intermediate filaments |
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Focal Adhesions / Focal Contacts (Cell-ECM)
transmembrane protein:: cytoskeletal connection:: |
INTEGRIN
F-actin (microfilaments) |
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Hemidesmosomes
transmembrane proteins:: cytoskeletal connection |
INTEGRIN
intermediate filaments |
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Gap Junctions
transmembrane proteins:: |
connexin
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low affinity, transient adhesion; made strong by increased numbers and density cell adhesion molecule
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integrins
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True or False
Integrins are dependent on divalent cations such as Ca2+ or Mg2+ |
True
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Integrins mostly link to ? cytoskeleton via linkers
hemidesmosomes however connect to ? |
ACTIN
intermediate filaments |
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True or False
IgSF-CAMS / I-CAMS are CALCIUM DEPENDENT |
FALSE
they are CALCIUM INDEPENDENT |
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True or False
Selectins are CALCIUM INDEPENDENT |
FALSE
they are CALCIUM DEPENDENT |
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SELECTINS are usually heterophilic interactions and bind to ? surface molecules
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carbohydrates
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? are for loose binding, especially between endothelium and various blood cells (CALCIUM DEPENDENT)
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selectin
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Where do you find PLASMA MEMBRANE INFOLDING?
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Basolateral Domain
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What type of collagen is the BASAL LAMINA made up of?
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TYPE IV collagen
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? anchors epithelia to basal lamina
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Laminin (glycoprotein)
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The attachment of CT to basal lamina is called the ?
and is made up of ? |
Reticular Lamina
TYPE III collagen (reticular fibers) TYPE VII collagen (anchor) Fibrillin (attach to elastic fibers) |
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Attachment of epithelium to basal lamina includes:
FOCAL ADHESIONS -- HEMIDESMOSOMES -- |
actin filaments via INTEGRINS and actin-binding linker proteins
intermediate filaments via TYPE XVII collagen and INTEGRINS |
