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12 Cards in this Set
- Front
- Back
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A-16. INF-a and INF-B use what cell types to induce MHC-1 and stop viral mRNA translation?
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INF-a: macrophages, TCs, BCs, granulocytes
INF-B: fibroblasts |
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A-16. What is the difference between Hodgkin's Disease and Non-Hodgkin Lymphome?
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HD: spreads in contiguity, no leukemic component, Reed-Sternberg cells
NHL: does NOT spread contiguity, often has a leukemic component in the blood, recently has become more common |
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A-16. What are the antibodies associated with Monoclonal Gammopathy, Mult. Myeloma, and Waldenstrom's?
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MG: usually IgG or IgA
MM: usually IgG or IgA Waldenstrom's: ALWAYS IgM |
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A-16. What are the key feature of Monckeberg's arterosclerosis?
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Media calcific stenosis, "gooseneck lumps", small and medium sized arteries, asymptomatic
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A-16. What is the pathogenesis of arteriosclerosis?
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1.) Injury to vascular endothelium 2.) lipids and platelets adhere to damaged surface 3.) Leukocytes and platelets release growth factors --> smooth muscle proliferation 4.) Macrophages become Foam Cells 5.) Foam cells aggregate to "fatty streaks", the beginning formation of an atherosclerotic plaque
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A-16. What are the key features of Giant Cell Arteritis?
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*TEMPORAL ARTERY, sudden blindness, female>male, a/w polymyalgia rheumatica
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A-16. What are the key feature of syphilitic aneurysms?
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Saccular
Ascending aorta a/w aortic insufficiency |
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A-16. Aortic regurgitation occurs in _______ and sounds like_______?
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"water hammer pulse" and sounds like a diostolic murmur and "pistol shots" in the femoral artery
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A-16. What are the acyanotic (L to R) congenital heart defects?
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VSD, ASD (ostium primum & secundum), PDA
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A-16. What makes up the Tetralogy of Fallot?
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1.) pulmonary art. stenosis 2.) overriding aorta 3.) VSD 4.) right ventricular hypertrophy
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A-16. What are the signs and tx of unstable angina?
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At rest or crescendo like, often leads to MI, unresponsive to nitro
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A-16. What is the most common cause of death following an MI?
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Arrhythmias
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