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22 Cards in this Set

  • Front
  • Back
What is preferential: laminar or turbulent flow?
Laminar flow, sometimes known as streamline flow, occurs when a fluid flows in parallel layers, with no disruption between the layers.
What is the formula for flow?
Q = V/T = volume/time
With the same flow (Q), if radius increases what happens to velocity?
Velocity decreases.
How is turbulent flow mathematically calculated?
Renold's number Nr = pDV/n

p = fluid density
D = vessel diameter
V = mean velocity
n = fluid viscosity
What values of Rn indicate laminar and turbulent flow?
Rn < 2000 = laminar flow
2000 < Rn < 3000 transitional
Rn > 3000 = turbulent flow
How does fluid density, vessel diameter, mean velocity, and fluid viscosity relate to turbulence?
Nr = pDV/n

/\ fluid density (p) -> /\ turbulence
/\ diameter (D) -> /\ turbulence
/\ mean velocity (V) -> /\ turbulence
/\ fluid velocity -> \/ turbulence
What is flow?
Q = (Pi-Po)/R

delPressure/Resistance
What is CO with regard to flow and pressure?
(MAP-RAP)/Rtpr

RAP = Mean Right Atrial Pressure

TPR = total peripheral resistance
What factor changes resistance the most?
vessel radius because R is inversely proportional to r^4
What is Poiseuilles' Law?
Q = (pi)*(Pi-Po)*(r^4)/(8nl)

know how changes in left affect right
How do you calculate total peripheral resistance?
TPR = (MAP-RAP)/CO
What is the total resistance of a series arrangement of individual resistances?
the sum of the resistances which will increase overall resistance
What is the total resistance of a parallel arrangement of individual resistances?
1/R = 1/R(n) + 1/R(n+1) + .....

which will decrease overall resistance
How does one estimate MAP?
diastolic P + 1/3*PP

so for 150/90, diastolic P = 90, PP = 150-90 = 60

MAP = 90+60/3 = 110
What causes an elevated MAP?
/\ CO or /\ TPR

use (MAP-RAP) = CO*TPR
(assume negligible RAP)
If brachial pressure is 150/90mmHg, then what is MAP?
What are the two possibilities to produce this pressure?
MAP = diastolic P+1/3PP
=90+(150-90)/3 = 110 mmHg

/\ CO, /\ R as TPR
For this pt, if normal CO is 5L/min and MAP normally is 90, then is CO or TPR the problem for him if the MAP is 110mmHg?
Calc normal TPR
TPR = MAP/CO = 90/5

Calc pts TPR @ MAP=110mmHg
TPR = MAP/CO = 110/5

So the problem is that the TPR is high.
If a pt has brachial P = 160/100 mmHg and the CO = 6 L/min, what is the R? What is the pts problem/why are they hypertensive? Note that for this pt, normal TPR ~ 20 mmHg/L/min.
MAP = 100+60/3 = 120 mmHg
TPR = MAP/CO = 120/6 = 20 mmHg/L/min (normal)

so the problem is /\ CO
If a pt has high output what are the possibilities of preload, afterload, and contractility?
/\ preload, \/ afterload, /\ contractility
What is the R for organ 1 and for organ 2?
R1 = P/Q = 100/300 = 1/3
R2 = P/Q = 100/500 = 1/5
MAP = 100 mmHg
Venous P = 2 mmHg
Qrest = 100 ml/min
Qexercise = 200 ml/min
What is Rrest? Rexercise? Why is it different?
Rrest = P/Qrest = 100/100 = 1
Rexercise = P/Qexercise = 100/200 = 0.5

vasodilation
What is the Fick method?
O2 consumed/{arteriole O2 - venous O2)*100 =
VO2/([CaO2]-[CvO2])*100 = L/min

Fick method in which the cardiac output is calculated as the quotient of oxygen uptake (O2) and the difference of the arterial and mixed venous oxygen content.