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7 Cards in this Set
- Front
- Back
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A-14. What are the key feature of G6PD Deficiency?
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-Hemolysis during oxidative stress, dehydration, acidosis
-Vaso-occlusive crisis -Aplastic crisis -Sequestration crisis (splenomegaly) -Autosplenectomy |
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A-14. Compare warm vs cold immune mediated deficiency.
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-Warm: usually IgG, active at 37C, caused by drugs, malignancies, and SLE
-Cold: usually IgM, most active at 0-4C, caused by mycoplasma pneumonia, mononucleosis, lymphoma "God likes it WARM" "Mary hates the COLD" |
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A-14. What is the difference between folate and B12 deficiencies in megaloblastic anemia?
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Both cause anemia, however, B12 with present with neurological symptoms
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A-14. Basostippling is a sign of....?
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Lead posioning
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A-14. What agents can cause neutropenia?
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Alkylating agents
Chloramphenicol Chlorpromazine Sulfonamides Phenylbutazone |
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A-14. What are the similarities and differences of Bruton's and Common Variable immunodeficiencies?
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Both cause bacterial infections. BCs are absent in Bruton's but present in CV (however produce few ABs)/ Bruton's is X-linked and CV is variable
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A-14. What is the pathophys of Vit. K deficiency and presentation?
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Decrease in factors, 2,7,9, and 10. Cause increased PTT and normal bleeding time
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