Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
What are some of the viral properties of HIV?
|
ss + RNA, enveloped,
|
|
|
What is the primary receptor of HIV?
|
CD4
|
|
|
What are some coreceptors for HIV?
|
CCR5 β-chemokine receptor (monocytes and macrophages, M-tropic) & CCR4 α-chemokine receptor (T lymphocytes, T-tropic)
|
|
|
What particular protein of HIV binds CD4?
|
gp120
|
|
|
What HIV protein mediates fusion with the host cell?
|
gp41
|
|
|
What feature of HIV DNA allows integration into the host genome?
|
LTRs
|
|
|
Where does HIV virus replicate in the latent state?
|
lymphoid tissue (CD4 T cells)
|
|
|
What is one of the mechanisms by which HIV evades an antibody response?
|
antigenic drift in the gp120 protein
|
|
|
What are some antigens that are tested for in HIV?
|
p24 (core protein), gp41, gp120
|
