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24 Cards in this Set
- Front
- Back
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? is a rare disease that is manifested by upper Gi tract ulceration , increased gastric acid secretion, and onr or more duodenal or pancreatic tumors, called ?
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Zollinger-Ellison syndrome(ZES)
gastrinomas |
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ZES is caused by ? secretin tumors that stimulate the acid-secreting cells of the ? to maximal activity.
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gastrin,
stomach |
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? results from the inactivation of pancreatic lipase secondary to the large concentrations of acid and decreased amounts of ? acids
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Steatorrhea,
bile |
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Infection with ? is usually absent in ZES.
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H.pylori
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The aim of treatment for ZES is to control ?
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symptoms
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? are the drug of choice to reduce gastric acid secretion and heal ulcers. High doses of ? are also effective in reducing gastric acid and providing symptom relief.
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PPI's,
H2-receptor antagonist |
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The tumors in ZES require complete ? resection as a curative treatment.
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surgical
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In some pts with ZES a ? procedure is performed which a radical ?
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whipple,
pancreaticoduodenectomy |
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Most cancers of the stomach are ?
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adenocarcinomas
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Often with gastric cancer there are ? symptoms in the early stages and the disease is ? when detected.
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no,
advanced |
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Pts with aggresive forms of ZES can be treated with ? agents.
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chemotherapeutic
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Gastric cancer usually begins in the ? of the stomach mucosa.
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glands
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Atrophic gastritis and intestinal metaplasia are ? conditions.
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precancerous
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Inadequate acid secretion in pts with atrophic gastritis creates an ? environment that allows bacteria especially H.pylori, to multiply.
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alkaline
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? spread via the portal vein to the liver and via the systemic circulation to thelungs and bones is the most common mode of metastasis from the stomach.
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hematogenous
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pts that eat ?,?,or ? foods have a greater risk for stomach cancer.
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pickled,
salted, smoked |
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? represents pronounced dilation, thickening of the stomach wall, or pyloric obstruction.
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vomiting
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In pts with advanced CA anemia is evidenced by low ?/? values. Pts may have macrocytic or microcytic anemia associated with decreased ? or ? absorption.
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Hgb/Hct,
iron, B12 |
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In stomach CA pts the stool may be + for OB.
? and abnormal resluts of liver tests(bilirubin&alkaline phosphate) occur with advanced disease and with hepatic metastasis. |
hypoalbuminemia
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The HCP use ? with biopsy for definitive diagnosis of stomach CA
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EGD esophagogastroduodenoscopy.
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?,?,? scans of the chest , abdomen, and pelvis are used in detrmining the extent of the gastric CA and planning therapy.
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CT,
PET, MRI |
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For non-surgical treatment of gastric CA combination ? with mutiple cycles of drugs such as ? and ? before and after surgry may be given.
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chemotherapy,
cisplatin, epirubicin |
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Alkaline reflux gastropathy, also known as bile reflux gastropathy is a complication of gastric surgery, in which the? is bypassed or removed.
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pylorus
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? loop syndrome may occur when the duodenal loop is partially obstructed after radical surgery.
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Afferent
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