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17 Cards in this Set

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Eosinophilia:
type I hypersensitivity, invasive helminths, hypocortisolism
B cells have:
CD21 receptor sites for EBV
Heterophile antibodies:
IgM antibodies directed against horse, sheep, bovine RBCs
Lymphopenia in HIV:
lysis of CD4 helper T cells by the virus
Corticosteroids produce:
neutrophilic leukocytosis, eosinopenia, and lymphopenia
Myeloid disorders:
neoplastic stem cell disorders
RBC count=
RBC mass/PV
Relative polycythemia:
increase RBC count; decrease PV; normal RBC mass, SaO2, EPO
Appropriate absolute polycythemia:
increase RBC mass, EPO; normal PV; decrease SaO2
Inappropriate absolute polycythemia (ectopic secretion EPO):
increase RBC mass, EPO; normal PV, SaO2
Polycythemia vera:
only type of polycythemia with increase PV and decrease EPO
AML:
auer rods in the cytoplasm of myeloblasts
ALL:
CD10 and TdT positive
Acute lymphoblastic (early pre-B type):
Newborn to 14 years old. CALLA (CD10) and TdT positive. t(12;21) offers a good prognosis
Chronic lymphocytic:
Virgin B cell leukemia. Most common cause of generalized lymphadenopathy. Hypogammaglobulinemia
Adult T cell:
HTLV-1 association. Leukemic cells CD4 positive and TdT negative. skin infiltration. lytic bone lesions with hypercalcemia
Hairy Cell:
B cell leukemia. Cytoplasmic projections. TRAP stain positive. Splenomegaly. Absence of lymphadenopathy. Pancytopenia. Dramatic response to purine nucleosides.