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37 Cards in this Set

  • Front
  • Back
bind with receptor for therapeutic effect
bind with receptor to prevent actions of agonist
absorption, distribution, metabolism, and excretion
process of getting drug into the blood stream/body
transport of drug through the body to the site of action
how drug is changed chemically to facilitate excretion
how drug leaves the body
therapeutic index
range of drug dosage that causes desired effect in body
low index
narrow margin of safty
high index
wide margin of safety
peak drug level
highest plasma concentrations @ a specific time
trough level
lowest plasma concentration @ a specific time
loading dose
large initial dose given to quickly raise plasma concentrations
maintenance dose
the amount of the drug prescribed to maintain a therapeutic level on a daily basis
effect greater than both drugs sum (potentiates the effect) 1+1=>2
combination of 2 drugs = efcect is doubled
one drug interferes with the action of another, diminishes or neutralizes
allergic reaction
antigen antibody reaction with release of histamine
drug idiosyncracy
(unpredictable) usually abnormal reaction
drug tolerance
decrease response to the drug-requires a larger dose for the same action
body can't metabolize the whole dose, build up, s&s of overdose
toxic reactions
negative effect from too much drug
side effects
known action that canoccur other than desired effect
action causing defects during fetal development
large number of drugs taken by one patient 7+
legend (caution) drugs
drugs that are not included in the CSA
body;s ablility to identify and protect itself against microorganisms that are potentially harmful
humoral immunity
process of creating antibodies by the lymphocythes
cell-mediated immunity
results of activity of T-lymphocytes
active immunity
there is a response, body forms antibodies
naturally acquired active immunity
get the disease and body makes antibodies in response to the dsease
artificaially acquired active immunity
body makes antibodies in response to an injected antigen (vaccine or toxin)
passive immunity
this is a gift of antibodies given to you
naturally acquired passive immunity
antibodies passed across the placenta
artificially acquired passive immunity
injection of antibodies for temporary protection
attenuated antigen
weakened live microorganism
dead antigen
contains proteins of microorganism