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51 Cards in this Set

  • Front
  • Back
What are the actions of antineoplastic agents
interfere with cell metobolism or division of cells
Name the cells that have a high mitotic activity
bone marrow, lymph tissue, GI tract, hair follicles and skin, gonads
What are the main adverse effects of the GI with antineoplastic agents
N/V/A, stomatitis, dry mouth and decreased saliva
What are the main adverse effects of Red bone Marrow with antineoplastic agents
decrease in platelets, WBC, and RBC
At what platlet count dose one stop antineoplatstic therapy
platlets are <80,000= stop therapy
At what WBC count dose one stop antineoplastic therapy
WBC are <4,000=cut dose 50%
WBC are <2,500=Stop therapy
Nursing Implications for N/V/A with antineoplastic agents
Keep pt. well hydrated Rx. 2-3L/day
I/O- watch for dehydration
lubricate lips
Nursing Implications for Stomatitis, xerostomia with antineoplastic agents
soft toothbrush, cold/cool fluids foods, bland food, artificial tears
Nursing Implications for Diarrhea with antineoplastic agents
I/O- check for blood in stool, antidiarrheal agents
Nursing Implications for alopecia with antineoplastic agents
warn pt. about hair loss/will grow back
Nursing Implications for Bone marrow depression with antineoplasic agents
Watch for infections, temp>101, reverse isolation, check WBCs, bleeding, brusing... NO NSAIDS
inhibits bacterial growth
causes bacteria to die
broad spectrum antibiotic
effective against wide variety of microorganisms
narrow spectrum antibiotic
effective against very selected (specific) microorganism
Name the adverse effects of antibiotics
Hypersensitivity (allergy), Resistance, superinfections
Nursing implications for allergies to antibiotics
Know allergies, assess for reactions, treat w/antihistamines
Nursing implications for bacterial resistance to antibiotics
teach pt. how/when to take Rx, to finish Rx, C&S, and report if pt. Sx are not getting better
Nursing implications for superinfections with antibiotics
C&S for new antibiotic, eat yogurt or take acidophilus capsules
What are the antibiotics that are better taken with an empty stomach
Tetracyclines, sulfa, pencillin, INH, Rifampin
penicillin V (Pen-Vee K)
peniclillin G (Bicillin, Wycilllin)
amoxicillin (Augmentin, Trimox)
methicillin (Staphcillin)
ampicillin (Unasyn)
What are the side effects of penicillins
allergy, GI- N/V/D
Nursing Implications for penicillins
COMPLIANCE, empty stomach W/water, notify Dr. if S&S of allergies occur
cephalexin (Keflex)
cefaclor (Ceclor)
cefatoxin (Calforan)
ceftriaxone (Rocephin)
cefixime (Suprax)
What are the side effects for cephalosporins
GI- N/V/D W/food, Nephrotoxic, supress bone marrow
Nursing Implications for cephalosporins
take w/food, FF because of neprotoxicity, cross reactions w/penicillin
ciprofloxacin (Cipro)
levofloxacin (Levaquin)
erythromycin (E-Mycin, EES)
erythiromycin estotate (Ilosone)
clarithromycin (Biaxin)
azithromycin (Zithromax)
Macrolides (erythromycins) a penicillin alternative
What are the side effects for macrolides
Abdominal cramping, N/V/D
Nursing Implications for macrolides
Use w/caution with pt. with liver disease
doxycyline (Vibramycin)
tetracycline (Achromycin)
What are the uses for tetracyclines
Chronic bronchitis, acne, prophylactic UTI, STDs
What are the side effects for tetracylines
high risk for superinfections, decreases RBC & WBS, and may interfer w/anticoagulents
Nursing Implications for tetracylines
advoid milk, cause photosensitivity, not for children <8yrs, GI-upset so FF, check kidney function, avoid w/pregnancy
gentamycin (Garacycin)
kanamycin (Kantrex)
Aminoglycosides (narrow spec)
What are the uses for aminoglycosides
IV for systemic effect on gram negative bacteria, serious infections
Nursing Implications for aminoglycosides
Check peak and troughs
Nephrotoxic- BUN, I/O, FF
Ototoxic, vertigo, hearing loss
Assess for superifections
(pseudomembranous colitis)
trimethoprim & sulfamethoxazol (Septra, Bactrim)
sulfamethoxzale (Gantanol, Azogantoanol)
mafenide (Sulfamylon)
What are the uses for Sulfonamides
UTIs, Otitis media, burns, prep for surgery
What are the side effects for sulfonamides
decreases RBCs, WBCs, Platelets
Nursing Implications for sulfonamides
crystalluria- FF >2000mL/24hr
I/O, w/empty stomach, avoid w/anticids, photosensitivity
amantadine (Symmetrel)
acyclovir (Zovirax)
zidovudine (AZT)
Antiviral agents
The use for Interferon
Gives boost to body's immunity (AIDS, MS)
The use for amantadine (symmetrel)
effective against Influenza A
The use for acyclovir (Zovirax)
Herpes simplex
The use for zidovudine (AZT)
treat patients ifected with HIV to improve QOL
tolnaftate (Tinactin)
nystatin (Mycostatin)
miconazole (Monistat)
amphotericin B (Fungizone)
metronidazole (Flagyl)
Anifungal agents
Use for antifungals
Local infections- topical treatments
Systemic infections- Metronidazole (Flagyl) *very toxic
Nursing Implications for antifungals
Instruct about application
I/O- monitor kidney function
*severe reaction w/alcohol
ethambutal (Myambutol)
isoniazid (INH)
rifampin (Rifadin)
Antitubercular agents
What are the side effects of antitubercular agents
paresthesia of extremeties, decrease in RR, seizures