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10 Cards in this Set
- Front
- Back
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H2 antagonists
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Ranitidine
Cimetidine Famotidine Nizatidine |
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H2 antagonists Indications
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Peptic ulcer disease
GORD Dyspepsia + Stress ulcer prophylaxis (ranitidine) |
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H2 antagonists SE
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hypotension
blood dyscrasias skin rashes headache tiredness confusion + gynaecomastia (cimetidine) |
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H2 antagonists Counselling
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! if symptoms do not improve after 2 weeks of treatment, see your doctor
! if nausea, severe vomiting, epigastric pain, black or bloodstained stools are experienced during or after treatment, seek medical advice 5 - cimetidine interacts with many drugs (e.g. warfarin, phenytoin, carbamazepine, prednisolone and theophylline). Check with your pharmacist or doctor before starting any other medications |
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PPIs
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Omeprazole
Esomeprazole Pantoprazole Rabiprazole Lasoprazole |
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PPIs Indications
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PUD, GORD, dyspepsia,
H. pylori eradication |
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PPIs SE
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WT
headache n/v diarrhoea abdo pain dizzy,fatigue flatulence, constipation DEC. vit B12 absorption + rhinitis, cough (R) |
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PPI Counselling
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A
! see doctor immediately if experience black stools or coffeecoloured vomit omeprazole tablets and esomeprazole capsules may be dispersed in water, drink immediately ! gastric pH can dec. Abs of azole/dig omeprazole increases plasma conc. of phenytoin and warfarin + mix with juice (L, P) + sucked then swallowed (L) |
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PPI Monitoring
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Sx control and Tx continuation
- Vit D and Ca levels if Tx >1yr |
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Nexium/Klacid HP7
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PPI 20mg (omeprazole, esomeprazole)
Amoxicillin 500mg Clarithromycin 500mg 1 bd |
