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12 Cards in this Set

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A-100. Patient is diagnosed with esophageal Camdida infection and an Cryptococcus neoformans infection. What two drugs will treat both?
Fluconazole and Amphotericin B
A-100. This drug inhibits translocation on 50s and this one inhibits peptidyl transferase on 50s.
Erythromycin

Chloramphenicol
A-100. These three cancer drugs affect folate synthesis.
Methotrexate

Trimethoprim

Pyrimethamine
A-100. Actinomycin D binds to DNA and inhibits________ at low [ ] and__________at high [ ]
Transcription

Replication
A-100. Hodgkin's Dz is treated with ABVD. What are those drugs?
A: adriamycin

B: bleomycin

V: vinblastine

D: dacarbazine
A-100. Why would you not give a child asprin?
Chance of getting Rye's Syndrome

Fulminating hepatitis and cerebral edema
A-100. Fatty acid synthesis, gluconeogensis, heme synthesis, AA synthesis, urea synthesis, and cholesterol synthesis all take place in the?
Liver
A-100. High Km =

A low Km =
HIgh: low affinity

Low: high affinity
A-100.Define gluconeogenic and ketogenic.
Gluco: carbon skeleton can be converted to glucose

Ketogenic:carbon skeleton can be converted to acetyl CoA
A-100. What AAs is tyrosine a precursor for?
Dopa/dopamine

Norepinephrine

Epinephrine

T3/T4

Melanin
A-100. Your patient has hyperreflexia and sweet smelling urine. You other other one has bad arthritis and dark urine. What dz/defect do they have?
Hyperreflex: "Maple Syrup" - defect in branched chain decarboxylase.

Dark: Alkaptonuria - defect in homogentisate oxidase
A-100. A patient has galactosemia. What enzyme is defected and how would they present?
Uridyltransferase

Cataracts and mental retardation