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39 Cards in this Set

  • Front
  • Back
Midazolam
Notes
Onset 2-5m
Propofol
Notes
Pain on injection, emulsion, elim via redist., ↓ PONV & BP
Etomidate
Notes
Induction Drugs
Ketamine
Notes
lasts 1 hour, "Special K", deriv.
of PCP
Sodium Thiopental
Notes
Will burn b / c high pH of 10 v.
pH of blood 7.4;
Garlic Taste
Succinylcholine
Notes
Onset: 60sec
Duration: 3-5 min
Causes Fasciculations
Rocuronium
Notes
Onset: 1-2 min
Duration: 20-35min
Vecuronium
Notes
onset 3-5 m
Duration: 20-35 min
Cisatracurium
Notes
Onset: 3-5 min
Duration: 20-35 min
Hoffman Elim.,not metab in liver / kidneys, use for pt w / renal disease
Pancuronium
Notes
Onset: 3-5 min
Duration: 60-90 min
Long duration, Hepatic / Renal Elim.
Atracurium
Notes
Onset: 3-5 min; Duration 20-35 min
Morphine
Notes
IV / IM, low lipid solubility-->slower onset(15-30m), Potency 1, 2-10mg peak effect 45-90m, duration 3-4h, metab.
in liver / kidnerys, active metabolite almost as potent as morphine, so will accumulate & last longer in pt w / kidney / renal disease.
Fentanyl
Notes
VERY lipid soluble & protein bound, can do IV,transdermal or PO, Peak effect 3-5m, duration 30-60m, 75% undergoes 1st pass pulmonary uptake / metab., Hemodynamic stability(doesn't cause histamine release), Drug interactions (can dec.
inhalation / induction agent dose req'd), can cause postop depression
Meperidine
Notes
Less potent than morphine (0.1 = potency)
Hydromorphone
Notes
synth heroine, long-term postop pain relief
Naloxone
Notes
Quick onset--1min
Isoflurane
Notes
Very stable CV changes-minimal at 1 Mac, smells bad
Desflurane
Notes
Highly insoluble-prompt recovery / emergence, Easily titratable due to high MAC
Sevoflurane
Notes
sweet smelling, least a / w irritant, used for inhalational inductions, particularly in pediatrics
Nitrous Oxide
Notes
Analgesic properties, sweet smelling, easy to breathe, remember ~ hypoxic mixture stuff; decrease amnt of inhaled anesthetic when using N2O b / c MACs additive, ↑ PONV???
Epinephrine
Notes
Sympathomimetics
Vasoactive Drugs
Ephedrine
Notes
works @ symp.
N terminal & releases norepinephrine to ↑BP
Phenylephrine
Notes
binds to α receptors to vasoconstrict "pipe"
Norepinephrine
Notes
Sympathomimetics
Vasoactive Drugs
Esmolol
Notes
Degraded by pseudocholinesterases, so fast off; selective for β1 receptors, Duration minutes
Metoprolol
Notes
pretty much same as Esmolol but Duration = hours
Labetolol
Notes
α1 and nonselective β1 & β2 antagonist; β:α = 7:1
Sodium Nitroprusside
Notes
short acting; light sensitive
Nitroglycerin
Notes
Dec Preload, dilate coronary arteries, fast on / fast off
Hydralazine
Notes
Onset 20m (slow), Duration 6-8 hours (time to raise bp back up in give too much),↑bld flow 2 head--> headache
Neostigmine
Notes
NMB Reversal Drugs
Glycopyrrolate
Notes
good for reversal b / c don't get a big ↑ in HR
Atropine
Notes
NMB Reversal Drugs
Ondansetron
Notes
1x dose, give 30m prior to end of case
Doperidol
Notes
1x dose, give 30m prior to end of case; works on Dopamine Receptors, so contraindicated in Parkinson pt
Lidocaine
Notes
Hepatic Clearance
Toxic Dose: 5mg / kg alone
7 mg / kg with Epi
Diphenhydramine
Notes
Hepatic Elimination
Heparin
Notes
Hepatic Elimination
Ketorolac
Notes
Renal Clearance, Postop Analgesic; avoid w / NSAID Allergy or recent hx GI bleeding