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20 Cards in this Set
- Front
- Back
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Which of the following is true regarding the physiologic effects of opioids?
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Constipation is the most common adverse effect of chronic opioid therapy
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Which of the following statements is TRUE regarding onset of opioid action
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The transmucosal route generally provides a faster onset than the oral route of administration.
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Kadian® is an example of an extended-release formulation of:
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Morphine
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When an opioid binds to receptors on presynaptic afferent neurons in the spinal cord:
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it decreases the release of neurotransmitters such as glutamate from these neurons
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Which of the following is an opioid that is more potent than morphine?
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Hydromorphone
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How do tolerance and physical dependence differ from addiction?
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Addiction is a behavioral pattern with genetic, psychosocial, and environmental factors influencing its development
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Most of the clinically available opioid medications act primarily by binding to what type of receptors?
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mu receptors
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Identify the correct statement regarding the following physiologic effects of opioids.
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Opioids cause nausea and vomiting due to effects on the vomiting center as well as effects in the gastrointestinal tract.
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Methadone is considered a ___________ opioid
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long-acting
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How long can the Duragesic® patch be worn before removal?
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72 hrs
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In general, continuous, dull pain is relieved more effectively than sharp or intermittent pain. (T or F)
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TRUE
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Equianalgesic dose of an opioid? (def)
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The dose that produces the same effect as 10 mg morphine administered parenterally or 30 mg or 60 mg morphine administered orally
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When a Schedule II opioid is prescribed:
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no refills are allowed, but the prescriber may provide several prescriptions with future dates that total 90 day supply.
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When an opioid binds to its receptor on presynaptic neurons, an action that closes calcium channels, what is the result?
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It reduces neurotransmitter release.
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Morphine and hydromorphone are classified as:
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opioid agonists
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A short-acting opioid may be appropriate when?
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Initiation of therapy
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Embeda contains .....
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morphine and naltrexone in an extended-release formulation
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Respiratory depression is due ....
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to the effects of opioids on the brain's respiratory center
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One risk of fixed-dose combinations containing acetaminophen is that increased doses may result in
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higher than recommended doses of acetaminophen, which is toxic to the liver
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Morphine and hydromorphone are examples of _______ drugs
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schedule 2
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