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25 Cards in this Set
- Front
- Back
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The spinothalamic tract...
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carries sensory impulses from the spinal cord to the brain
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What is radiculopathy?
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Injury to the nerve roots of the spine
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A ________ is a bundle of axons in the peripheral nervous system
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nerve
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Data from the National Health and Nutrition Examination Survey indicate that:
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the incidence of chronic pain is greatest in people greater than or equal to 65 years of age.
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________ transmit fast-sharp pain
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A axons
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Low back pain is an example of ________ pain
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chronic
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Endogenous opioids act ....
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In the spinal cord and the brain
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Describe the sequence of neurotransmission.
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Binding of neurotransmitters to receptors on the postsynaptic cell opens ion channels.
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List the characteristics of chronic pain
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- Can affect a person's ability to sleep and concentrate
- Cause may be unknown - May develop abruptly or gradually |
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What is substance P?
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A neurotransmitter involved in pain transmission
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A nociceptor is:
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a pain receptor
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List some characteristics of cancer pain
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- It can be either neuropathic or nociceptive.
- The actions of some chemotherapy agents can damage nervous tissue, resulting in pain. - It is one of the most common symptoms of cancer. |
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Describe pain impulse transmission
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In the dorsal horn, the A and C fibers transmit their impulses to an interneuron or a succession of interneurons.
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What does an afferent neuron do?
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A sends impulses from the peripheral nervous system to the central nervous system.
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What chronic pain conditions is the second most common reason for physician visits and the most common cause of job-related disability?
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Low back pain
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What is the dorsal root ganglion?
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cluster of cell bodies of sensory neurons just outside the spinal cord
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A visual analogue scale asks patients to
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B rate their pain on a numbered scale from 0 to 10
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Describe spinal gate pain inhibition.
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Impulses sent on large axons can suppress those sent on A and C axons
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When nociceptors detect a pain impulse, it triggers .....
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corresponding axons in the dorsal root ganglion to secrete enkephalin
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Traditionally, chronic pain has been defined as pain lasting:
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greater than or equal to 3 months or greater than or equal to 6 months
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It is thought that serotonin stimulates the _____________ in descending pain inhibition pathways.
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secretion of enkephalin by interneurons
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In the process of neurotransmission, when calcium ions flow into the axon terminal, it causes:
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neurotransmitters to be released from vesicles into the synaptic cleft.
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Somatic pain (def)
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Pain that arises from the skin, connective tissue, muscle, and bone
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What is thought to be the role of enkephalin in the descending pain inhibition pathway?
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Prevents A and C fibers from secreting substance P and other excitatory neurotransmitters
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Unipolar neurons (def)
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Neurons that have their dendrites and axon fused into a single extension from the cell body.
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