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11 Cards in this Set
- Front
- Back
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Whats a normal CD4 count?
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500-1500 cells/mm3
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At what CD4 count do the following infections come into play?
Mycobacterium TB Varicella Zoster Oral Candidiasis PCP Cryptooccal meningitic Cytomegalovirus MAC |
350
275 250 170 125 50 50 |
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When do you start proph for PCP?
What do you use for proph? what do you use for Tx? |
proph if CD4 < 200
prophylaxis with bactrim SS or DS -can also use dapsone, pentamidine treatment use Bactrim DS x 21 days and then SS (15-20mg/kg of TMP/day) Can use adjunctive corticosteroid therapy to decrease risk of respiratory failure (prednisone) |
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What do you treat with CMV?
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can start when CD4 < 50
CMV is most life threatening viral infection in patients with aids use Ganciclovir Foscarnet (only for HIV patients with retinitis and acyclovir resistant HSV) Cidofovir (CMV retinitis only) |
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Herpes treatment?
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acyclovir or
valacyclovir |
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Cryptococcal Meningitis treatment?
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AmpB w/wo flucytosine
then Fluconazole 400mg then fluconazole proph for life w 200mg daily |
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Toxoplasmosis treatment?
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PARASITE
Sulfadiazine + pyrimetamine + folinic acid or clindamycin |
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MAC treatment?
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1. clarithromycin (biaxin) or azithromycin (zithromax)
2. amikacin or cipro WITH ethambutol and rifabutin Prophylaxis if < 50cells/ azithromycin 1200 or rifabutin treatment is for remainder of life |
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Kaposi's sarcoma
what is it? Tx? |
malignant tumor usually involving the skin + commonly encountered HIV patinets
use daunorubicin (DaunoXome) can also use Alitretinoin - Panretin if no systemic therapy |
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What will probenacid do to Valacyclovir?
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decrease excretion
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famciclovir
uses |
famvir
uncomplicated VZV and HSV |
