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42 Cards in this Set

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Advantages of the use of vasoconstrictors

Prolongs action of anesthetic solution



Allows for lesser volume and conc to be used



Increases efficiency and safety

P A In

Conditions that may lead to complications (vasoconstrictors itu)

They were used in volumes that are too high



Repeated injection increases the volume



Intravascular injection may lead to elevated blood level to cause complications

They Re In

Modes of action of vasocontrictors

Attaching to and directly stimulating adrenergic receptors



Acting indirectly by stimulating release of endogenous catecholamine



Combination of direct and indirect action

D I C

Vasoconstrictor derivatives + example/s

Pyrocatechin - Epi & NE


Benzol - Levonoderfin


Phenol - Phenyldephrine

Most potent vasoconstrictor

Epinephrine

Effect/s of epinephrine to CVS

Beta1 stimulation increases heart rate & force of contraction



Increase in irritability of myocardium leading to an increased incidence of dysrhythmia



Large doses may increase BP

B I L

Effect/s of epinephrine to respi system

Pronounced bronchodilation

Effect/s of epinephrine to CNS

Stimulation produce alerting effects

Effect/s of epinephrine to respi system

Pronounced bronchodilation

Effect/s of epinephrine to CNS

Stimulation produce alerting effects

Misc effect/s of epinephrine

Elevation of blood sugar level



Increase glycogenolysis



Pupillary dilation

Other name of norepinephrine

Levophed

NE is a _____ found in _____

Major pressor amine



Post ganglionic nerves

NE is usually used in what conc?

1:30000

NE is a _____ found in _____

Major pressor amine



Post ganglionic nerves

NE is usually used in what conc?

1:30000

Effect/s of norepinephrine to CVS

Increase HR SV FoC



Increase myocardium irritability lead to greater incidence of cardiac dysrhythmias



Producing elevated BP

NE is a _____ found in _____

Major pressor amine



Post ganglionic nerves

Effect/s of norepinephrine to respi sys

No effect (kasi predominantly alpha si NE)



Produces alpha induced constriction of the kung arterioles which reduces airway resistance to a small degree

N P

Effect/s of norepinephrine to CNS

Mild alerting effects (on higher dosage of NE)

Conc of levonordefrin

1:10000

Levonordefrin can be tx to

Neuralgia

Weakest vasoconstrictor in dentistry

Phenylephrine

Effect/s of phenylephrine to CVS

Increase BFlow im coronary arteries as result of dilation



Cause increase in BP

Weakest vasoconstrictor in dentistry

Phenylephrine

Effect/s of phenylephrine to CVS

Increase BFlow im coronary arteries as result of dilation



Cause increase in BP

Effect/s of phenylephrine to respi system

Bronchodilation milder than epi

Toxic manifestations to vasoconstrictors (in order)

Tachycardia


Hypertension


Palpitation


Headache


Tremors


Pallor


Ventricular fibrillation

Ta Hy Pal He Tre Pallo Ven

Termination of action of vasoconstrictors

Reuptake by the nerve terminal



Deactivation of extraneuronal enzymes (COMT)



Uptake by the bloodstream



Intraneuronal enzymatic destruction by MAO

Re De Up In

General armamentaria for LA

Needle


Anesthetic cartridges


Syringes


Auxillary materials

NASA

Parts of a needle

Bevel


Shank/shaft


Hub


Cartridge part (or syringe penetrating end)


Syringe adaptor

Be Sha Hu Ca Sy Sy

Basically the jxn bet needle and syringe


where needle usually breaks

Hub

Refers to the diameter of the needle

Gauge

Usual gauge in dentistry

25 & 27

Usual bevel in needle

65degrees

The term carpule is actually a registered trade name by

Cook-Waite Laboratories

Standard volume of cartridges

1.8mL

Parts of a cartridge

Cylinder glass tube


Stopper (plunger)


Aluminum cap


Rubber diaphragm

Cy S A R

Contents of cartridges (LA) + rationale

Vasocontrictors - for analgesia



Anesthetic drugs - to increase safety and duration of LA



Sodium bisulfite - preservative of vasoconstrictors



Methylparaben - antimicrobial (NOT USED ANYMORE DOE)



Distilled water - to achieve desired volume



Sodium chloride - to make solution isotonic


V A So


M D S

Possible problems on cartridges

Bubble (presence of nitrogen)



Extruded plungers (prolonged exposure to disinfectants)



Corrosion of aluminum caps (bec of disinfectants rin)

Problems with syringe handling

Leakage during injection



Cartridge breaking



Disengagement of harpoon during aspiration



Surface deposits



(See trans nalang for the rationale)

Le Ca Di Su

Aux material for LA

Oxygen tank