Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
|
How does Rapoport-Leubering shunt affect RBC metabolism?
|
Decreases ATP yield, because need to lose high energy phosphate to form 3-PG (with 2,3BPG as intermediate)
|
|
|
PPP oxidative phase produces how much NADPH?
|
2 NADPH
|
|
|
PK deficiency results in what disease? What is the functional deficit?
|
hemolytic anemia. cannot make enough atp from pyruvate.
|
|
|
With G6PD deficiency, which cells must be assayed?
|
older mature cells (young reticks give higher read).
|
|
|
Which drugs should be avoided in G6PD deficiency?
|
antimalarials, sulfonimides, antibacterials, analgesics, antihelminths (oxidators)
|
|
|
What is the inheritance of G6PD deficiency?
|
x-linked recessive
|
