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adenosine alternate name alternate name

Adenocard

Adenosine classification

Antidysrhythmic

Changes heart rhythms

Adenosine mechanism of action

Adenosine is a naturally occurring nucleoside that can Convert paroxysmal supraventricular tachycardia (PSVT) to a normal sinus rhythm by blocking conduction through the atrioventricular AV node. It has a half life of 10 seconds and does not cause hypotension.

Adenosine indications

Conversion of paroxysmal supraventricular tachycardia psvt to sinus rhythm, May convert reentry supraventricular tachycardia SVT due to Wolf Parkinson's White wpw syndrome. Does not convert atrial fibrillation or atrial flutter or ventricular tachycardia.

Adenosine contraindications

Second or third degree heart block or sick sinus syndrome, afib/ flutter, v-tach, hypersensitivity to adenosine, poison induced tachycardia.

Adenosine precautions

May cause transient dysrhythmia such as prolong sinus arrest. Can induce bronchoconstriction in asthmatics and COPD patients. Lower doses may be an effective if patient on Theophylline or excessive caffeine. Very short half-life, about 10 to 12 seconds, so must be given rapid IV push in the most proximal Port followed immediately by saline flush. Pregnancy category C.

Adenosine adverse effects

Facial flushing, chest pain, Headache, nausea, hypotension.

Adenosine dosage /route

Adult: 6 mg rapid IV / 1 to 3 seconds, followed by 20 ml saline flush, if no response after 1 to 2 minutes, repeat with 12 mg / 1 to 3 seconds to a maximum dose of 30 mg.


Pediatric: 0.1 to 0.2 mg per kg rapid IV maximum single dose 12 mg.

Amiodarone alternate names

Cordarone, pacerone

Amiodarone classification

Antidysrhythmic

Amiodarone mechanism of action

Block sodium and potassium channels of myocardial cells dust affecting the action potential of the cell. Prolongs the duration of the action potential and refractory period and relaxes smooth muscles, reducing peripheral vascular resistance and increasing coronary blood flow.

Amiodarone indications

v-fib, pulseless v-tach and unstable v-tach, persistent supraventricular tachycardia is unresponsive to other treatment.

Amiodarone contraindications

Known hypersensitivity, cardiogenic shock, sinus bradycardia, and second or third degree AV block.

Amiodarone precautions

Hepatic impairment, pregnancy, nursing mothers, children.

Amiodarone adverse effects

Hypotension, bradycardia, prolongation of the pr, QRS, and QT intervals.

Amiodarone dosage and route

Adult. V-fib, pulseless v-tach unresponsive to CPR, defibrillation, vasopressors. 300 mg IV or IO push recommended dilution in 20 to 30 ml D5W. Repeat at 1/2 does after 3 to 5 minutes. Ventricular arrhythmias. Infuse 150 mg IV IO over 10 minutes 15 mg per minute. May repeat every 10 minutes to a maximum dose of 2.2 grams in 24 hours.


Pediatric refractory v-fib, pulseless v-tach. 5 mg per kilogram IV IO bolus. Can repeat this dose up to 15 mg per kg per 24 hours. Max dose of 300 mg.


Perfusing svt's and v-tach. Loading dose of 5 mg per kilogram I VI o over 20 to 60 minutes with a Max single dose of 300 mg. Can repeat to Max of 15 mg per kilogram per day.

Acetylsalicylic acid names

Aspirin, asa,enpirin, gen pirineo, Bayer, Norwich extra strength, st Joseph's adult, ecotrine, halfprin 81,heartline, zorprin, easprin, asaphen, entrophen, novasen.

Acetylsalicylic acid classification

NSAID, Platelet aggregation inhibitor

Activated charcoal classification

Absorbant

Activated charcoal moa

Activated charcoal is a specially prepared charcoal that would resorb and bind toxins from the gastrointestinal tract

Activated charcoal indications

Most oral poisonings and medication overdoses, can be used after evacuation of poisons.

Activated charcoal contra

None reported

Activated charcoal precaucion

Not recommended for poisonings due to cyanide, iron, lithium, lead, or arsenic. Does not absorb. Used cautiously with ingestion of corrosive, petroleum distillates, caustics, organic solvents, May induce vomiting leading to aspiration.

Activated charcoal dose

Adult 25 to 100 G orally. Pediatric 1 to 2 grams per kilogram. Can be used in conjunction with cathartic, magnesium citrate or sorbitol.

Albuterol names

Proventil, Ventolin

Albuterol classification

Bronchodilator, sympathomimetic

Albuterol moa

Selective beta 2 Agonist that induces bronchodilation by relaxation of smooth muscles in the bronchial tree. Onset of action via inhalation is 5 to 15 minutes with a duration of 3 to 6 hours.

Albuterol indications

To control bronchospasm in patients with reversible obstructive airway disease, COPD, asthma. Prevention of exercise induced bronchospasms.

Albuterol contraindications

known hypersensitivity.

Albuterol precautions

Used cautiously in cardiac disease, hypertension, hypothyroidism, diabetes, seizure disorder, patients with tachyarrhythmia is taking Digoxin, safety not established for pregnant patients near-term, breastfeeding, and children less than 2 years old.

Albuterol adverse reactions

Restlessness, Tremors, nervousness, paradoxical bronchospasm, chest pain, tachycardia, nausea and vomiting, hyperglycemia

Albuterol dose/routes

Adults and children over 12 years old, 2.5 mg added to 2 ml of normal saline for inhalation buy nebulizer, repeat every 20 minutes up to three times, metered dose inhaler. 1 to 2 inhalations or 90 to 100 micrograms, 5 minutes between inhalations. Pediatric ages 2 to 12, administer 0.15 mg per kilogram per dose every 20 minutes for a maximum of 3 doses

Aspirin names

Acetylsalicylic acid, Alka-Seltzer, Bayer, empirin, St Joseph's children's, and many other compounds.

Aspirin classification

Salicylate, platelet inhibitor, anti-inflammatory

Aspirin mechanism of action

Prostaglandin inhibition, aspirin inhibits agents that cause the production of inflammation, pain, and fever, and inhibits platelet aggregation.

Aspirin indications

New onset chest pain suggestive of acute myocardial infarction, recent cerebrovascular accidents.

Aspirin contraindications

Hypersensitivity, relatively contraindicated in patients with active peptic ulcer disease, allergy to other NSAIDs medication, and bleeding disorders.

Aspirin precautions

Children or teenagers with varicella or influenza-like symptoms, increases the risk of Reye's syndrome. Pregnancy category D.

Aspirin adverse effects

GI bleeding, nausea and vomiting.

Aspirin dose route

Adult. 160 mg to 325 mg mg orally, chewed if possible. Pediatric, not recommended.

Dextrose name

D50W

Dextrose classification

Carbohydrate, hypertonic solution.

Dextrose mechanism of action

Rapidly increases serum glucose levels. Short-term osmotic diuresis

Dextrose indications

Hypoglycemia, altered level of consciousness, seizure or coma of unknown etiology, status epilepticus.

Dextrose contraindications

Intracranial hemorrhage.

Dextrose precautions

Increased intracranial pressure. Determine blood glucose level before Administration. Drug interaction with sodium bicarbonate and Coumadin. Administering thiamine prior to D50 and known alcoholics and, encephalopathy.

Dextrose adverse effects

Extravasation leads to tissue necrosis, ensure good IV access. Pain and burning at IV site. Phlebitis.

Dextrose dose route

Adult. 12.5 to 25 grams slow IV, may be repeated as necessary, 25g D50 W 50 ml IV. Pediatric. 0.5 to 1 gram per kilogram per dose slow IV, may be repeated as necessary, for infants and small children use a 10% or 25% solution.

Epinephrine names

Adrenaline

Epinephrine classification

Sympathomimetic

Epinephrine moa

Non-selective Alpha and beta adrenergic Agonist. A naturally occurring catecholamine that increases heart rate, chronotropy, cardiac contractile Force, inotropy, myocardial electrical activity, dromotropy, increases systemic vascular resistance, and systolic blood pressure, and decreases overall Airway resistance. It also, through bronchial artery constriction, May reduce pulmonary congestion and increase tidal volume and vital capacity.

Epinephrine indications

Cardiac Arrest, ventricular fibrillation, pulseless ventricular tachycardia, assist Ali, and p e a. Anaphylaxis and allergic reactions. Symptomatic bradycardia, when atropine and transcutaneous pacing do not work. Severe hypotension, as an alternative to dopamine. Asthma, allergic reactions

Epinephrine contra

Hypertension, hypothermia, pulmonary edema, myocardial ischemia, hypovolemic shock.

Epinephrine precautions

Elderly, debilitated patients, hypertension history, diabetes, hyperthyroidism, Parkinson's

Epinephrine adverse effects

Nervousness, Tremor, angina, arrhythmia, hypertension, tachycardia, hyperglycemia, paradoxical bronchospasm.

Epinephrine dose route

Cardiac arrest. Follow ACLS guidelines, 1mg, 10 mL of a 1 to 10 solution every three to five minutes during resuscitation.



Asthma and allergic reactions. 0.3 to 0.5 mg or 0.3 t o 0.5 milliliters of a 1 to 1000 concentration subcutaneous.


Anaphylaxis. 0.1 mg or 1 ml of 1 to 10,000 solution IV IO over 5 minutes. Follow each dose with 20 flush and Elevate arm for 10 to 20 seconds after dose. Higher dose, up to 0.2 mg per kg may be used for specific indications such as calcium channel blocker or beta blocker overdose.


Pediatric, follow Pals guidelines.



Cardiac arrest. 0.01 mg per kilogram or 0.1 ml per kilogram of a 1 to 10,000 solution IV IO dose.


Anaphylaxis, 0.01 mg per kilogram or 0.1 ml per kilogram are they 1 to 10000 solution IV IO every 3 to 5 minutes if hypotension is present maximum dose of 1mg or 0.01 mg per kilogram, 0.01 ml per kilogram of a 1 to 1000 solution every 15 minutes as needed maximum dose of 0.3 mg intramuscular.


Shock, I VI o continuous infusion of 0.11 microgram per kilogram per minute.


Asthma and Mild allergic reactions. 0.01 mg per kg subcut, 0.01 ml per kilogram of a 1 to 1000 solution every 3 to 5 minutes maximum dose of 1mg.

Diphenhydramine name

Benadryl

Diphenhydramine classification

Antihistamine/anticholinergic

Diphenhydramine mech of action

Blocks cellular histamine release (H1); decreases vasodilation; reverses extrapyradimal reactions.

Diphenhydramine indications

Anaphylactic reactions; Allergic reactions ; dystonic reactions ; motion sickness ; hay fever.

Diphenhydramine contraindications

Asthma, glaucoma, infants, pts taking MAOI drugs.

Diphenhydramine precautions

Pregnancy B, potentiates effects of alcohol and anticholinergic drugs.

Diphenhydramine adverse effects

Hypotension, sedation and drowsiness, headache, dizziness, excitable state (children), blurred vision, dry mouth.

Diphenhydramine dose/route

Adults: 25-50mg IV/IM/PO



PEDI: 1-2mg/kg IV/IO slowly


PO dose is 5mg/kg/24hr

Haloperidol (Haldol) classification

Tranquilizer, antipsychotic

Activated charcoal dose

(Adult) 25-100gm PO


(PEDI) 1-2gm/kg

Albuterol dose

(Adult) >12y/o: 2.5mg nebulizer repeat every 20min x3


(PEDI) .15mg/kg/dose

Aspirin dose

(Adult) 160-325 mg po chewed


(PEDI) not recommended

Glucagon dose

(Adult) hypoglycemic 0.5-1.0 mg/kg IM (may repeat in 7-10min)


Calcium channel/beta blocker OD :3mg followe by 3mg/hr infusion


(PEDI) 0.5-1mg IM

Atrovent

(Adult) 500mcg nebulizer every 6-8hr


(PEDI) not recommended

Noxolone

(Adult) 0.4-2.0 mg IV/IO/IM/ET


Infusion 2mg/500ml D5W 0.4mg/hr


(PEDI) 0.1mg/kg max 0.8mg repeat in 10 for effect

Nitroglycerin dose

(Adult) 0.4 mg SL every 3-5min x3


Infusion 10-20mcg/min increase 5/10mcg every 5min for effect.

Nitro paste dose

1/2 to 1 in strip

Oral glucose dose

Sip slowly till clinical improvement


(15mg?)