Mitosis is a process of cellular division. What happens though when Mitosis (process of cellular division) goes wrong? You can get a disease from Mitosis going wrong, some very bad ones too. A widely known disease caused by cellular division going wrong is Cancer and Tumors.
(1)Disrupted passage through mitosis often leads to chromosome missegregation and the production of aneuploidy progeny. Aneuploidy has long been seen as a frequent characteristic of cancer cells. Also Aneuploidy has been seen as a frequent characteristic of tumorigenesis.
Mitotic spindle assembly are drugs that are frequently used to treat various types of human tumors. These lead to chronic mitotic arrest if they are sustained from the activation of mitotic checkpoint. …show more content…
He discovered that the progeny produced contained abnormal numbers of chromosomes. That condition was known as aneuploidy. In that time aneuploidy was already known to be a common characteristic of tumors. Boveri having discovered this proposed that aneuploidy progeny produced from a disrupted mitosis became the progenitor cells of tumors. However the original hypothesis remains untested so it is assumed that there is a link between mitosis, aneuploidy, and cancer.
(2)Although mitosis has potential to cause tumorigenesis, mitosis has served as a successful antitumor target. Drugs that arrest cells in mitosis, they are known as antimitotic, have become the common treatment for various kinds of human tumors. An Antimitotic can be used to treat breast cancer, ovarian cancer, and also non-small-cell lung
(1)Disrupted passage through mitosis often leads to chromosome missegregation and the production of aneuploidy progeny. Aneuploidy has long been seen as a frequent characteristic of cancer cells. Also Aneuploidy has been seen as a frequent characteristic of tumorigenesis.
Mitotic spindle assembly are drugs that are frequently used to treat various types of human tumors. These lead to chronic mitotic arrest if they are sustained from the activation of mitotic checkpoint. …show more content…
He discovered that the progeny produced contained abnormal numbers of chromosomes. That condition was known as aneuploidy. In that time aneuploidy was already known to be a common characteristic of tumors. Boveri having discovered this proposed that aneuploidy progeny produced from a disrupted mitosis became the progenitor cells of tumors. However the original hypothesis remains untested so it is assumed that there is a link between mitosis, aneuploidy, and cancer.
(2)Although mitosis has potential to cause tumorigenesis, mitosis has served as a successful antitumor target. Drugs that arrest cells in mitosis, they are known as antimitotic, have become the common treatment for various kinds of human tumors. An Antimitotic can be used to treat breast cancer, ovarian cancer, and also non-small-cell lung