Vibrio Cholera Research Paper

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The Blue Death is a mortifying illness that in most cases leads to death within a few days. Cholera is a severe dehydrating disease caused by vibrio cholerae, that affects victims worldwide. It is nicknamed The Blue Death, due to the extreme loss of fluids the body turns bluish-gray color. It is an acute diarrheal disease that causes severe vomiting and diarrhea. The first pandemic occurred in South Asia, in 1817 and continued to spread throughout India, China, the Middle East and Japan. It also spread to Europe due to the trading and exportation of goods. Once this disease hit Europe, it was able to spread faster due to the major waterways and railroads that were industrialized during that time. According to World Health Organization, 100,000 to 120,000 people die each year and three to five million people are infected a year (Daniel, 2017) .
The development of cholera is very important to understand how the disease evolves. Vibrio cholerea is a gram-negative bacillus, facultative anaerobe that can survive in water or under halophilic conditions for
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The major symptoms include diarrhea, nausea, vomiting, and dehydration. Other symptoms and signs may consist of muscle cramps, abdominal cramping, dry skin, irregular heartbeat, low blood pressure, little urine output and dry mucous membranes inside the mouth, throat, eyelids, or nose (“Cholera,” 2005) . The major treatment for cholera is rehydration therapy because dehydration can lead to shock and death within a few hours. It is important to prompt restoration of lost fluids and salts. There are several antibiotics that are effective in helping decrease the fluid requirements and period of illness, such as Azithromycin, Tetracycline, Doxycycline and several others. There is also a vaccine available, but the World Health Organization does not actually recommend it because once you get the vaccine it only lasts a few days (“Cholera,” 2005)

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