Functions of protein TP53
TP53 has a general name called tumor suppressor protein p53. Tp53 has many names such as phosphoprotein p53, cellular tumor antigen p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53). Also, TP53 has also been referred to as the guardian of the genome [19]. In 1979, scientists first observed the gene by using SDS-PAGE and found it has a size of about 53-kilodalton (kDa). The location of the TP53 gene is at chromosome 17, at position 13.1. [11]. TP53 has 393 amino acids. TP53 has many important functions in the body. These functions play a role in genomic stability, apoptosis, and inhibition of angiogenesis. TP53 can be active and will respond to the exposure of toxic metals,
TP53 has a general name called tumor suppressor protein p53. Tp53 has many names such as phosphoprotein p53, cellular tumor antigen p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53). Also, TP53 has also been referred to as the guardian of the genome [19]. In 1979, scientists first observed the gene by using SDS-PAGE and found it has a size of about 53-kilodalton (kDa). The location of the TP53 gene is at chromosome 17, at position 13.1. [11]. TP53 has 393 amino acids. TP53 has many important functions in the body. These functions play a role in genomic stability, apoptosis, and inhibition of angiogenesis. TP53 can be active and will respond to the exposure of toxic metals,